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    STP2 Stp2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856397, updated on 2-Nov-2024

    Summary

    Official Symbol
    STP2
    Official Full Name
    Stp2p
    Primary source
    SGD:S000001048
    Locus tag
    YHR006W
    See related
    AllianceGenome:SGD:S000001048; FungiDB:YHR006W; VEuPathDB:YHR006W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See STP2 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (117814..119439)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene protein transporter TIM10 Neighboring gene tRNA-Thr Neighboring gene sterol 14-demethylase Neighboring gene uncharacterized protein

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Stp2p
    NP_011870.1
    • Transcription factor; activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes; STP2 has a paralog, STP1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      117814..119439
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179136.1NP_011870.1  TPA: Stp2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011870.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DKV0, E9P956, P38704
      UniProtKB/TrEMBL
      B3LSC6, C8ZA73
      Conserved Domains (2) summary
      sd00017
      Location:206226
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:204226
      zf-C2H2; Zinc finger, C2H2 type