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    RLP24 ATPase-activating ribosome biosynthesis protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850695, updated on 2-Nov-2024

    Summary

    Official Symbol
    RLP24
    Official Full Name
    ATPase-activating ribosome biosynthesis protein
    Primary source
    SGD:S000003999
    Locus tag
    YLR009W
    See related
    AllianceGenome:SGD:S000003999; FungiDB:YLR009W; VEuPathDB:YLR009W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables ATPase activator activity. Involved in assembly of large subunit precursor of preribosome. Located in nucleolus. Part of preribosome, large subunit precursor. Orthologous to human RSL24D1 (ribosomal L24 domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See RLP24 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (166537..167136)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Smc5-Smc6 complex subunit NSE1 Neighboring gene Pam18p Neighboring gene Ten1p Neighboring gene tRNA-Ser

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATPase activator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in assembly of large subunit precursor of preribosome IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in ribosomal large subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosomal large subunit biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of preribosome, large subunit precursor HDA PubMed 
    part_of preribosome, large subunit precursor IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    ATPase-activating ribosome biosynthesis protein
    NP_013109.1
    • Essential protein required for ribosomal large subunit biogenesis; associated with pre-60S ribosomal subunits; stimulates the ATPase activity of Afg2p, which is required for release of Rlp24p from the pre-60S particle; has similarity to Rpl24Ap and Rpl24Bp

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      166537..167136
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181896.1NP_013109.1  TPA: ATPase-activating ribosome biosynthesis protein [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013109.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VY11, Q07915
      UniProtKB/TrEMBL
      A7A0R4, B3LSY2, B5VMV1, C7GPE9, C8ZCY1, G2WIK3, N1NYZ6
      Conserved Domains (1) summary
      pfam01246
      Location:264
      Ribosomal_L24e; Ribosomal protein L24e