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    MRM1 Mrm1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854376, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MRM1
    Official Full Name
    Mrm1p
    Primary source
    SGD:S000005727
    Locus tag
    YOR201C
    See related
    AllianceGenome:SGD:S000005727; FungiDB:YOR201C; VEuPathDB:YOR201C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    PET56
    Summary
    Enables rRNA (guanine-N1-)-methyltransferase activity. Involved in rRNA modification. Located in mitochondrion. Orthologous to human MRM1 (mitochondrial rRNA methyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MRM1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (720470..721708, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Ca(2+)-dependent cysteine protease MCA1 Neighboring gene Bfr1p Neighboring gene imidazoleglycerol-phosphate dehydratase HIS3 Neighboring gene DEAD-box ATP-dependent RNA helicase DED1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Poly(dA).poly(dT) rich sequences are not sufficient to exclude nucleosome formation in a constitutive yeast promoter. Losa R, et al. Nucleic Acids Res, 1990 Jun 25. PMID 2194162, Free PMC Article
    2. Nucleotide sequence and transcriptional mapping of the yeast pet56-his3-ded1 gene region. Struhl K. Nucleic Acids Res, 1985 Dec 9. PMID 3001645, Free PMC Article
    3. Constitutive and inducible Saccharomyces cerevisiae promoters: evidence for two distinct molecular mechanisms. Struhl K. Mol Cell Biol, 1986 Nov. PMID 3540601, Free PMC Article
    4. The role of nucleotide modifications in the yeast mitochondrial ribosome. Sirum-Connolly K, et al. Nucleic Acids Symp Ser, 1995. PMID 8643404
    5. Functional requirement of a site-specific ribose methylation in ribosomal RNA. Sirum-Connolly K, et al. Science, 1993 Dec 17. PMID 8266080

    See all (51) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables rRNA (guanine) methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables rRNA (guanine-N1-)-methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in gene expression IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in rRNA methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in rRNA modification IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA modification IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Mrm1p
    NP_014844.3
    • Ribose methyltransferase; modifies a functionally critical, conserved nucleotide in mitochondrial 21S rRNA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      720470..721708 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183620.3 → NP_014844.3  TPA: Mrm1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014844.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2Q8, P25270
      UniProtKB/TrEMBL
      A6ZP45, B5VS84, C7GWI0, N1NX53
      Conserved Domains (1) summary
      TIGR00186
      Location:123 → 412
      rRNA_methyl_3; rRNA methylase, putative, group 3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P25270.2

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