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    RNH70 Rnh70p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853193, updated on 9-Dec-2024

    Summary

    Official Symbol
    RNH70
    Official Full Name
    Rnh70p
    Primary source
    SGD:S000003508
    Locus tag
    YGR276C
    See related
    AllianceGenome:SGD:S000003508; FungiDB:YGR276C; VEuPathDB:YGR276C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    REX1; RNA82
    Summary
    Enables 3'-5'-RNA exonuclease activity. Involved in RNA 3'-end processing. Located in nucleus. Orthologous to human REXO1L1P (REXO1 like 1, pseudogene) and REXO1 (RNA exonuclease 1 homolog). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See RNH70 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (1043819..1045480, complement)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene histone acetyltransferase Neighboring gene Rtt102p Neighboring gene putative pantetheine-phosphate adenylyltransferase Neighboring gene U2-type spliceosomal complex subunit CWC22

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables 3'-5' exonuclease activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables 3'-5'-RNA exonuclease activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables exonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Rnh70p
    NP_011792.1
    • 3'-5' exoribonuclease; required for maturation of 3' ends of 5S rRNA and tRNA-Arg3 from dicistronic transcripts

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      1043819..1045480 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181405.1NP_011792.1  TPA: Rnh70p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011792.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VV53, P53331
      UniProtKB/TrEMBL
      B3LHW8, C7GNF9, C8Z9G9, N1P2R2
      Conserved Domains (1) summary
      cd06145
      Location:226374
      REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins