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    HMS1 Hms1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854197, updated on 9-Dec-2024

    Summary

    Official Symbol
    HMS1
    Official Full Name
    Hms1p
    Primary source
    SGD:S000005558
    Locus tag
    YOR032C
    See related
    AllianceGenome:SGD:S000005558; FungiDB:YOR032C; VEuPathDB:YOR032C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable DNA-binding transcription activator activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in pseudohyphal growth. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See HMS1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (389771..391075, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Dfg16p Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene Rad2 family nuclease EXO1

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in pseudohyphal growth IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Hms1p
    NP_014675.1
    • bHLH protein with similarity to myc-family transcription factors; overexpression confers hyperfilamentous growth and suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      389771..391075 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183451.1NP_014675.1  TPA: Hms1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014675.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W297, Q12398
      UniProtKB/TrEMBL
      G2WMR2, N1P2Y6
      Conserved Domains (1) summary
      cd11399
      Location:265363
      bHLHzip_scHMS1_like; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Saccharomyces cerevisiae transcription factor HMS1 and similar proteins