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    MFM1 Mfm1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856045, updated on 9-Dec-2024

    Summary

    Official Symbol
    MFM1
    Official Full Name
    Mfm1p
    Primary source
    SGD:S000005981
    Locus tag
    YPL060W
    See related
    AllianceGenome:SGD:S000005981; FungiDB:YPL060W; VEuPathDB:YPL060W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    LPE10
    Summary
    Enables magnesium ion transmembrane transporter activity. Involved in mitochondrial magnesium ion transmembrane transport. Located in mitochondrial inner membrane. Orthologous to human MRS2 (magnesium transporter MRS2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See MFM1 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (434523..435764)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene aldehyde dehydrogenase (NADP(+)) ALD6 Neighboring gene tRNA-Cys Neighboring gene gag-pol fusion protein

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    Mfm1p
    NP_015265.1
    • Mitochondrial inner membrane magnesium transporter; involved in maintenance of mitochondrial magnesium concentrations and membrane potential; indirectly affects splicing of group II introns; functionally and structurally related to Mrs2p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      434523..435764
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183874.1NP_015265.1  TPA: Mfm1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015265.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W3V4, Q02783, Q6B1B1
      UniProtKB/TrEMBL
      C7GTZ6, G2WPB9
      Conserved Domains (1) summary
      cd12823
      Location:74395
      Mrs2_Mfm1p-like; Saccharomyces cerevisiae inner mitochondrial membrane Mg2+ transporters Mfm1p and Mrs2p-like family