SXM1 Sxm1p [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: SXM1
Official Full Name: Sxm1p
Primary source: SGD:S000002803
Locus tag: YDR395W
See related: AllianceGenome:SGD:S000002803; FungiDB:YDR395W; VEuPathDB:YDR395W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as: KAP108
Summary: Enables nuclear import signal receptor activity. Involved in mRNA export from nucleus and protein import into nucleus. Located in cytoplasm and nucleus. Orthologous to human IPO8 (importin 8). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome IV - NC_001136.10 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables nuclear import signal receptor activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables nuclear import signal receptor activity	IPI Inferred from Physical Interaction more info	PubMed
enables nuclear import signal receptor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables small GTPase binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in import into nucleus	IEA Inferred from Electronic Annotation more info
involved_in intracellular protein transport	IEA Inferred from Electronic Annotation more info
involved_in mRNA export from nucleus	IGI Inferred from Genetic Interaction more info	PubMed
involved_in mRNA transport	IEA Inferred from Electronic Annotation more info
involved_in protein import into nucleus	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein import into nucleus	IDA Inferred from Direct Assay more info	PubMed
involved_in protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nuclear envelope	IBA Inferred from Biological aspect of Ancestor more info
part_of nuclear pore	IEA Inferred from Electronic Annotation more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info

NP_010683.3

Nuclear transport factor (karyopherin); involved in protein transport between the cytoplasm and nucleoplasm; similar to Nmd5p, Cse1p, Lph2p, and the human cellular apoptosis susceptibility protein, CAS1

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The following sections contain reference sequences that belong to a specific genome build. Explain