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    SLIRP2 SRA stem-loop interacting RNA binding protein 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41021, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SLIRP2provided by FlyBase
    Official Full Name
    SRA stem-loop interacting RNA binding protein 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0037602
    Locus tag
    Dmel_CG8021
    See related
    AllianceGenome:FB:FBgn0037602
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg8021; CG8021; Dmel\CG8021; DmSLIRP2
    Summary
    Predicted to enable mRNA binding activity. Predicted to be active in nucleus. Orthologous to human SLIRP (SRA stem-loop interacting RNA binding protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See SLIRP2 in Genome Data Viewer
    Location:
    85A5-85A5; 3-48 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8651084..8651493)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4476806..4477215)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Cytochrome P450 313b1 Neighboring gene MAP kinase kinase 4 Neighboring gene Dihydroorotate dehydrogenase Neighboring gene Sys1 golgi trafficking protein Neighboring gene uncharacterized protein Neighboring gene belle

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation. Baggio F, et al. Nucleic Acids Res, 2014 Dec 16. PMID 25428350, Free PMC Article
    2. Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. Mummery-Widmer JL, et al. Nature, 2009 Apr 23. PMID 19363474, Free PMC Article
    3. Genome-wide RNAi screen identifies networks involved in intestinal stem cell regulation in Drosophila. Zeng X, et al. Cell Rep, 2015 Feb 24. PMID 25704823, Free PMC Article
    4. The drosophila melanogaster genome: translation factors and RNA binding proteins. Lasko P. J Cell Biol, 2000 Jul 24. PMID 10908586, Free PMC Article
    5. Screen for mitochondrial DNA copy number maintenance genes reveals essential role for ATP synthase. Fukuoh A, et al. Mol Syst Biol, 2014 Jun 21. PMID 24952591, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of mitochondrial transcription IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in mitochondrial matrix IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SRA stem-loop interacting RNA binding protein 2
    Names
    CG8021-PA
    SLIRP2-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      8651084..8651493
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141551.2 → NP_649808.1  SRA stem-loop interacting RNA binding protein 2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649808.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3DNE9, Q9VHP3
      Related
      FBpp0081367
      Conserved Domains (1) summary
      cd12242
      Location:11 → 83
      RRM_SLIRP; RNA recognition motif found in SRA stem-loop-interacting RNA-binding protein (SLIRP) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VHP3 Q9VHP3

    Gene LinkOut

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