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    Cyp6a9 Cytochrome P450 6a9 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36663, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cyp6a9provided by FlyBase
    Official Full Name
    Cytochrome P450 6a9provided by FlyBase
    Primary source
    FLYBASE:FBgn0013771
    Locus tag
    Dmel_CG10246
    See related
    AllianceGenome:FB:FBgn0013771
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    6a9; CG10246; Cyp6A9; CYP6a9; CYP6A9; Cyt-P450-rAF4; Dmel\CG10246; P-450; P450
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cyp6a9 in Genome Data Viewer
    Location:
    51D1-51D1; 2-73 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14879356..14881372, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10766861..10768877, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Cytochrome P450 6a17 Neighboring gene Cytochrome P450 6a23 Neighboring gene Cytochrome P450 6a19 Neighboring gene Cytochrome P450 6a20 Neighboring gene Cytochrome P450 6a21

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation and sequence analysis of cytochrome P450 12B1: the first mitochondrial insect P450 with homology to 1 alpha,25 dihydroxy-D3 24-hydroxylase. Danielson PB, et al. Insect Biochem Mol Biol, 1997 Jun. PMID 9304797
    2. Cytochromes P450 and insecticide resistance. Scott JG. Insect Biochem Mol Biol, 1999 Sep. PMID 10510498
    3. Cytochrome P450 monooxygenases and insecticide resistance in insects. Bergé JB, et al. Philos Trans R Soc Lond B Biol Sci, 1998 Oct 29. PMID 10021770, Free PMC Article
    4. Three second chromosome-linked clustered Cyp6 genes show differential constitutive and barbital-induced expression in DDT-resistant and susceptible strains of Drosophila melanogaster. Maitra S, et al. Gene, 1996 Nov 21. PMID 8973362
    5. Insect cytochromes P450: diversity, insecticide resistance and tolerance to plant toxins. Scott JG, et al. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol, 1998 Nov. PMID 9972456

    See all (58) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450 6a9
    Names
    CG10246-PB
    Cyp6a9-PB
    cytochrome P450 related AF4
    cytochrome P450-6a9
    NP_523748.2
    • non-AUG (AUA) translation initiation, point mutation, may be evolving pseudogene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      14879356..14881372 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079024.3 → NP_523748.2  cytochrome P450 6a9 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523748.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q27594, Q8MRY8, Q9V772
      Conserved Domains (1) summary
      pfam00067
      Location:35 → 499
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q27594.3 Q27594

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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