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    CG8414 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36774, updated on 17-Dec-2024

    Summary

    Official Symbol
    CG8414provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034073
    Locus tag
    Dmel_CG8414
    See related
    AllianceGenome:FB:FBgn0034073
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8414; NOL9
    Summary
    Predicted to enable ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity. Predicted to be involved in cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be active in nucleus. Is expressed in several structures, including anterior endoderm; embryonic/larval midgut; embryonic/larval midgut primordium; larval muscle system; and mesoderm. Orthologous to human NOL9 (nucleolar protein 9). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See CG8414 in Genome Data Viewer
    Location:
    52E4-52E5; 2-77 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (16099306..16102608, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (11986811..11990113, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43415 Neighboring gene Dystroglycan Neighboring gene mitochondrial ribosomal protein L34 Neighboring gene Rho1 Neighboring gene Ras-related protein interacting with calmodulin

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables polynucleotide 5'-hydroxyl-kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables polynucleotide 5'-hydroxyl-kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables polynucleotide 5'-hydroxyl-kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in rRNA processing ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG8414-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      16099306..16102608 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137240.4NP_611084.2  uncharacterized protein Dmel_CG8414 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611084.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A1ZA92, Q8SZP4
      UniProtKB/TrEMBL
      V5LWT6
      Related
      FBpp0086393
      Conserved Domains (3) summary
      pfam07382
      Location:41163
      HC2; Histone H1-like nucleoprotein HC2
      pfam11705
      Location:255333
      RNA_pol_3_Rpc31; DNA-directed RNA polymerase III subunit Rpc31
      cl21455
      Location:639824
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases