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    CG12071 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43660, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12071provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039808
    Locus tag
    Dmel_CG12071
    See related
    AllianceGenome:FB:FBgn0039808
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12071
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12071 in Genome Data Viewer
    Location:
    100A6-100A6; 3-101 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30877084..30881027, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (26702806..26706749, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Saposin-related Neighboring gene Cytochrome P450 4c3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The insulator protein Suppressor of Hairy-wing is an essential transcriptional repressor in the Drosophila ovary. Soshnev AA, et al. Development, 2013 Sep. PMID 23884443, Free PMC Article
    2. Mapping gene regulatory networks in Drosophila eye development by large-scale transcriptome perturbations and motif inference. Potier D, et al. Cell Rep, 2014 Dec 24. PMID 25533349
    3. Synergistic activation by Glass and Pointed promotes neuronal identity in the Drosophila eye disc. Wang H, et al. Nat Commun, 2024 Aug 17. PMID 39154080, Free PMC Article
    4. Genome-wide mapping of in vivo targets of the Drosophila transcription factor Kruppel. Matyash A, et al. J Biol Chem, 2004 Jul 16. PMID 15131112
    5. Notch and Ras signaling pathway effector genes expressed in fusion competent and founder cells during Drosophila myogenesis. Artero R, et al. Development, 2003 Dec. PMID 14602676

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12071-PD
    CG12071-PE
    CG12071-PF
    CG12071-PG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      30877084..30881027 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_176592.2 → NP_788769.2  uncharacterized protein Dmel_CG12071, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788769.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86PF2, Q95TD1, Q9VA29
      Conserved Domains (3) summary
      sd00017
      Location:187 → 207
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:185 → 207
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:200 → 224
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001316548.1 → NP_001303477.1  uncharacterized protein Dmel_CG12071, isoform F [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A126GV33
      Conserved Domains (3) summary
      sd00017
      Location:187 → 207
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:185 → 207
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:200 → 224
      zf-H2C2_2; Zinc-finger double domain

    3. NM_143575.4 → NP_651832.3  uncharacterized protein Dmel_CG12071, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651832.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86PF2, Q95TD1, Q9VA29
      Conserved Domains (3) summary
      sd00017
      Location:187 → 207
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:185 → 207
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:200 → 224
      zf-H2C2_2; Zinc-finger double domain

    4. NM_001316549.1 → NP_001303478.1  uncharacterized protein Dmel_CG12071, isoform G [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A126GV33
      Conserved Domains (3) summary
      sd00017
      Location:187 → 207
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:185 → 207
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:200 → 224
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A126GV33 A0A126GV33
    Q7K356 Q7K356
    Q9VA29 Q9VA29

    Gene LinkOut

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