U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    mus81 mus81 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31044, updated on 9-Dec-2024

    Summary

    Official Symbol
    mus81provided by FlyBase
    Official Full Name
    mus81provided by FlyBase
    Primary source
    FLYBASE:FBgn0040347
    Locus tag
    Dmel_CG3026
    See related
    AllianceGenome:FB:FBgn0040347
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3026; Dmel\CG3026; EG:BACR7A4.16; Mus81
    Summary
    Predicted to enable 3'-flap endonuclease activity. Predicted to contribute to crossover junction DNA endonuclease activity. Involved in DNA repair. Predicted to be part of Holliday junction resolvase complex. Predicted to be active in nucleus. Is expressed in organism and spermatozoon. Orthologous to human MUS81 (MUS81 structure-specific endonuclease subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See mus81 in Genome Data Viewer
    Location:
    1D2-1D2; 1-0 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (941075..943229)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (835108..837262)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene TRAM Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Bibliography

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables 3'-flap endonuclease activity  
    enables DNA binding  
    contributes_to crossover junction DNA endonuclease activity  
    enables crossover junction DNA endonuclease activity  
    Process Evidence Code Pubs
    involved_in DNA catabolic process  
    involved_in DNA repair PubMed 
    involved_in double-strand break repair  
    involved_in double-strand break repair via break-induced replication  
    involved_in mitotic intra-S DNA damage checkpoint signaling  
    involved_in resolution of meiotic recombination intermediates  
    Component Evidence Code Pubs
    part_of Holliday junction resolvase complex  
    is_active_in nucleus  

    General protein information

    Preferred Names
    mus81
    Names
    CG3026-PA
    mus81-PA

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      941075..943229
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130517.3 → NP_569873.1  mus81 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_569873.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V3T1
      Related
      FBpp0070165
      Conserved Domains (2) summary
      pfam02732
      Location:157 → 295
      ERCC4; ERCC4 domain
      cl11966
      Location:16 → 96
      NT_Pol-beta-like; Nucleotidyltransferase (NT) domain of DNA polymerase beta and similar proteins
    External link. Please review our privacy policy.