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    Tango4 Transport and Golgi organization 4 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32168, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tango4provided by FlyBase
    Official Full Name
    Transport and Golgi organization 4provided by FlyBase
    Primary source
    FLYBASE:FBgn0030365
    Locus tag
    Dmel_CG1796
    See related
    AllianceGenome:FB:FBgn0030365
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1796; Dmel\CG1796; tango4; TANGO4
    Summary
    Involved in Golgi organization and protein secretion. Located in cytosol. Part of Prp19 complex. Is expressed in adult head and organism. Orthologous to human PLRG1 (pleiotropic regulator 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Tango4 in Genome Data Viewer
    Location:
    11A1-11A1; 1-38 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (12021068..12022746)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11915101..11916779)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene regucalcin Neighboring gene Chromatin accessibility complex 16kD protein Neighboring gene LSM12 homolog a Neighboring gene Ubiquitin-specific protease 7 Neighboring gene Cytochrome P450 311a1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein secretion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Prp19 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Prp19 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of catalytic step 2 spliceosome HDA PubMed 
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of precatalytic spliceosome HDA PubMed 

    General protein information

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    Preferred Names
    transport and golgi organization 4
    Names
    CG1796-PA
    Tango4-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      12021068..12022746
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132550.3 → NP_572778.1  transport and golgi organization 4 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572778.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VYQ9
      Related
      FBpp0073459
      Conserved Domains (3) summary
      COG2319
      Location:161 → 458
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:164 → 458
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:177 → 212
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VYQ9 Q9VYQ9

    Gene LinkOut

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