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    CG6398 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32761, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6398provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030870
    Locus tag
    Dmel_CG6398
    See related
    AllianceGenome:FB:FBgn0030870
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6398
    Summary
    Located in apical cortex. Is expressed in several structures, including adult head; dorsal ectoderm; dorsal ectoderm anlage; gut section; and mesoderm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6398 in Genome Data Viewer
    Location:
    16D5-16D7; 1-58 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (17830828..17841705)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (17724861..17735738)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Suppressor of Cytokine Signaling at 16D Neighboring gene long non-coding RNA:CR44691 Neighboring gene TBP-associated factor 9 Neighboring gene uncharacterized protein Neighboring gene Uncoupling protein 4A Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Drosophila Claudin Kune-kune is required for septate junction organization and tracheal tube size control. Nelson KS, et al. Genetics, 2010 Jul. PMID 20407131, Free PMC Article
    2. Transposition of the vertebrate Tol2 transposable element in Drosophila melanogaster. Urasaki A, et al. Gene, 2008 Dec 1. PMID 18775483
    3. Cis-regulatory variation is typically polyallelic in Drosophila. Gruber JD, et al. Genetics, 2009 Feb. PMID 19064705, Free PMC Article
    4. Organization and function of the blood-brain barrier in Drosophila. Stork T, et al. J Neurosci, 2008 Jan 16. PMID 18199760, Free PMC Article
    5. Sinuous is a Drosophila claudin required for septate junction organization and epithelial tube size control. Wu VM, et al. J Cell Biol, 2004 Jan 19. PMID 14734539, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    NOT involved_in establishment of glial blood-brain barrier IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical cortex HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in septate junction ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6398-PA
    CG6398-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      17830828..17841705
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298462.1 → NP_001285391.1  uncharacterized protein Dmel_CG6398, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285391.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VX17
      Conserved Domains (1) summary
      pfam13903
      Location:16 → 232
      Claudin_2; PMP-22/EMP/MP20/Claudin tight junction

    2. NM_133016.3 → NP_573244.1  uncharacterized protein Dmel_CG6398, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573244.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VX17
      Related
      FBpp0074236
      Conserved Domains (1) summary
      pfam13903
      Location:16 → 232
      Claudin_2; PMP-22/EMP/MP20/Claudin tight junction
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VX17 Q9VX17

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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