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    AVT2 Avt2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856645, updated on 9-Dec-2024

    Summary

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    Official Symbol
    AVT2
    Official Full Name
    Avt2p
    Primary source
    SGD:S000000790
    Locus tag
    YEL064C
    See related
    AllianceGenome:SGD:S000000790; FungiDB:YEL064C; VEuPathDB:YEL064C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Located in endoplasmic reticulum. Orthologous to human SLC38A11 (solute carrier family 38 member 11). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See AVT2 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (29797..31239, complement)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene D-amino-acid N-acetyltransferase Neighboring gene siderophore transporter Neighboring gene arginine permease CAN1 Neighboring gene nitrogen permease regulating protein NPR2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001137.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A family of yeast proteins mediating bidirectional vacuolar amino acid transport. Russnak R, et al. J Biol Chem, 2001 Jun 29. PMID 11274162
    2. Vacuolar amino acid transporters upregulated by exogenous proline and involved in cellular localization of proline in Saccharomyces cerevisiae. Nishida I, et al. J Gen Appl Microbiol, 2016 Jul 14. PMID 27246536
    3. Bootstrapping the interactome: unsupervised identification of protein complexes in yeast. Friedel CC, et al. J Comput Biol, 2009 Aug. PMID 19630542
    4. The yeast oligopeptide transporter Opt2 is localized to peroxisomes and affects glutathione redox homeostasis. Elbaz-Alon Y, et al. FEMS Yeast Res, 2014 Nov. PMID 25130273
    5. The phox homology (PX) domain protein interaction network in yeast. Vollert CS, et al. Mol Cell Proteomics, 2004 Nov. PMID 15263065

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables L-amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-alpha-amino acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in vacuolar membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in vacuole IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Avt2p
    NP_010850.1
    • Putative transporter; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      29797..31239 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178879.1 → NP_010850.1  TPA: Avt2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010850.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DLI6, P39981, Q2VQX2
      UniProtKB/TrEMBL
      A6ZQN7, N1P536
      Conserved Domains (1) summary
      pfam01490
      Location:65 → 467
      Aa_trans; Transmembrane amino acid transporter protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P39981.1

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