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    Lipt2 lipoyl(octanoyl) transferase 2 (putative) [ Mus musculus (house mouse) ]

    Gene ID: 67164, updated on 27-Dec-2024

    Summary

    Official Symbol
    Lipt2provided by MGI
    Official Full Name
    lipoyl(octanoyl) transferase 2 (putative)provided by MGI
    Primary source
    MGI:MGI:1914414
    See related
    Ensembl:ENSMUSG00000030725 AllianceGenome:MGI:1914414
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2610209A20Rik
    Summary
    Enables lipoyl(octanoyl) transferase activity. Involved in protein lipoylation. Located in mitochondrion. Orthologous to human LIPT2 (lipoyl(octanoyl) transferase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 29.8), colon adult (RPKM 15.1) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Lipt2 in Genome Data Viewer
    Location:
    7 E2; 7 54.33 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (99808484..99810138)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (100159277..100160931)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene polymerase (DNA-directed), delta 3, accessory subunit Neighboring gene STARR-positive B cell enhancer ABC_E3737 Neighboring gene predicted gene, 34760 Neighboring gene STARR-positive B cell enhancer ABC_E11740 Neighboring gene predicted gene, 51452 Neighboring gene predicted gene, 39057 Neighboring gene predicted gene, 34821 Neighboring gene potassium voltage-gated channel, Isk-related subfamily, gene 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables lipoyl(octanoyl) transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables lipoyl(octanoyl) transferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of oxygen metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of oxygen metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein lipoylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein lipoylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein lipoylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial
    Names
    lipoate-protein ligase B
    lipoyl/octanoyl transferase
    lipoyltransferase 2
    octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase
    putative lipoyltransferase 2, mitochondrial
    putative octanoyltransferase, mitochondrial
    NP_080286.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026010.2NP_080286.2  octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial

      See identical proteins and their annotated locations for NP_080286.2

      Status: VALIDATED

      Source sequence(s)
      AK008917, BC115472, BE648757
      Consensus CDS
      CCDS21494.1
      UniProtKB/Swiss-Prot
      Q14C29, Q9CVA5, Q9D009
      Related
      ENSMUSP00000032967.4, ENSMUST00000032967.4
      Conserved Domains (1) summary
      cl14057
      Location:1231
      BPL_LplA_LipB; Biotin/lipoate A/B protein ligase family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      99808484..99810138
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)