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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853658, updated on 9-Dec-2024

    Summary

    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000001705
    Locus tag
    YKL222C
    See related
    AllianceGenome:SGD:S000001705; FungiDB:YKL222C; VEuPathDB:YKL222C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables sequence-specific DNA binding activity. Predicted to be involved in DNA-templated transcription and regulation of transcription by RNA polymerase II. Located in mitotic spindle and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (3503..5620, complement)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene seripauperin PAU16 Neighboring gene Mch2p Neighboring gene ferric/cupric-chelate reductase

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific  
    enables metal ion binding  
    enables sequence-specific DNA binding PubMed 
    enables zinc ion binding  
    enables zinc ion binding PubMed 
    Component Evidence Code Pubs
    located_in mitotic spindle PubMed 
    located_in nucleus PubMed 
    located_in nucleus  

    General protein information

    Preferred Names
    uncharacterized protein
    NP_012700.1
    • hypothetical protein; may interact with ribosomes, based on co-purification experiments; similar to transcriptional regulators from the zinc cluster (binuclear cluster) family; null mutant is sensitive to caffeine

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      3503..5620 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179787.1 → NP_012700.1  TPA: uncharacterized protein YKL222C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012700.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VWY1, P35995
      UniProtKB/TrEMBL
      A7A067, B3LQN7, G2WHH2
      Conserved Domains (2) summary
      smart00066
      Location:18 → 59
      GAL4; GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain
      pfam04082
      Location:200 → 463
      Fungal_trans; Fungal specific transcription factor domain
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