U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Zfp383 zinc finger protein 383 [ Mus musculus (house mouse) ]

    Gene ID: 73729, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zfp383provided by MGI
    Official Full Name
    zinc finger protein 383provided by MGI
    Primary source
    MGI:MGI:1920979
    See related
    Ensembl:ENSMUSG00000099689 AllianceGenome:MGI:1920979
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110003H10Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nuclear membrane and nucleoplasm. Predicted to be active in nucleus. Is expressed in cerebral cortex ventricular layer. Orthologous to human ZNF383 (zinc finger protein 383). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in whole brain E14.5 (RPKM 5.0), CNS E14 (RPKM 4.9) and 19 other tissues See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Zfp383 in Genome Data Viewer
    Location:
    7 B1; 7 17.26 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (29607705..29616238)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (29908280..29916813)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10434 Neighboring gene zinc finger protein 420 Neighboring gene STARR-seq mESC enhancer starr_18494 Neighboring gene zinc finger protein 27 Neighboring gene STARR-positive B cell enhancer ABC_E9288 Neighboring gene microRNA 7668 Neighboring gene STARR-seq mESC enhancer starr_18496 Neighboring gene zinc finger protein 74 Neighboring gene RIKEN cDNA C230062I16 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:30738577-30738760 Neighboring gene STARR-positive B cell enhancer ABC_E8160 Neighboring gene predicted gene, 57504 Neighboring gene macrophage migration inhibitory factor, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001243908.1NP_001230837.1  zinc finger protein 383

      Status: VALIDATED

      Source sequence(s)
      AC149283
      Consensus CDS
      CCDS80690.1
      UniProtKB/TrEMBL
      A0A087WRR7
      Related
      ENSMUSP00000140742.2, ENSMUST00000186475.2
      Conserved Domains (6) summary
      smart00349
      Location:2787
      KRAB; krueppel associated box
      COG5048
      Location:246490
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:327347
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:437459
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:2766
      KRAB; KRAB box
      pfam13465
      Location:367392
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      29607705..29616238
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011250725.2XP_011249027.1  zinc finger protein 383 isoform X2

      Conserved Domains (5) summary
      smart00349
      Location:1272
      KRAB; krueppel associated box
      COG5048
      Location:231475
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:312332
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:170192
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:212237
      zf-H2C2_2; Zinc-finger double domain
    2. XM_006540391.1XP_006540454.1  zinc finger protein 383 isoform X1

      Conserved Domains (5) summary
      smart00349
      Location:3595
      KRAB; krueppel associated box
      COG5048
      Location:254498
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:335355
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:193215
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:235260
      zf-H2C2_2; Zinc-finger double domain