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    Mrgprb2 MAS-related GPR, member B2 [ Mus musculus (house mouse) ]

    Gene ID: 243979, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mrgprb2provided by MGI
    Official Full Name
    MAS-related GPR, member B2provided by MGI
    Primary source
    MGI:MGI:2441674
    See related
    Ensembl:ENSMUSG00000050425 AllianceGenome:MGI:2441674
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mgrg14; 4833406I20Rik
    Summary
    Predicted to enable G protein-coupled receptor activity and neuropeptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to several human genes including MRGPRX2 (MAS related GPR family member X2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See Mrgprb2 in Genome Data Viewer
    Location:
    7 B4; 7 31.11 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (48200713..48207834, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (48550965..48558086, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene MAS-related GPR, member B1 Neighboring gene MAS-related GPR, member X2 Neighboring gene STARR-seq mESC enhancer starr_18885 Neighboring gene MAS-related GPR, member B9, pseudogene Neighboring gene MAS-related GPR, member B3 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Clone Names

    • MGC130390, MGC130391

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables G protein-coupled receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables neuropeptide binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transmembrane signaling receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mas-related G-protein coupled receptor member B2
    Names
    Mas-related G protein-coupled receptor g14

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175531.4NP_780740.2  mas-related G-protein coupled receptor member B2

      See identical proteins and their annotated locations for NP_780740.2

      Status: VALIDATED

      Source sequence(s)
      AK029369, BC107391, BX519265
      Consensus CDS
      CCDS21303.1
      UniProtKB/Swiss-Prot
      Q3KNA1, Q8CDY4, Q91ZC2
      UniProtKB/TrEMBL
      W8W3G3
      Related
      ENSMUSP00000061878.2, ENSMUST00000052730.3
      Conserved Domains (1) summary
      pfam00001
      Location:55286
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      48200713..48207834 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)