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    Hmgn5 high-mobility group nucleosome binding domain 5 [ Mus musculus (house mouse) ]

    Gene ID: 50887, updated on 9-Dec-2024

    Summary

    Official Symbol
    Hmgn5provided by MGI
    Official Full Name
    high-mobility group nucleosome binding domain 5provided by MGI
    Primary source
    MGI:MGI:1355295
    See related
    Ensembl:ENSMUSG00000031245 AllianceGenome:MGI:1355295
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nsbp1; GARP45; NBP-45
    Summary
    Enables chromatin binding activity. Acts upstream of or within chromatin organization; glutathione metabolic process; and regulation of transcription by RNA polymerase II. Located in nucleoplasm. Is expressed in several structures, including 1st branchial arch; brain; genitourinary system; gut gland; and hemolymphoid system gland. Orthologous to human HMGN5 (high mobility group nucleosome binding domain 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in placenta adult (RPKM 39.8), CNS E11.5 (RPKM 28.7) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Hmgn5 in Genome Data Viewer
    Location:
    X D; X 47.92 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (108048143..108056986, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (109004537..109013380, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2810403D21 gene Neighboring gene STARR-positive B cell enhancer ABC_E5735 Neighboring gene capping protein (actin filament), gelsolin-like pseudogene Neighboring gene predicted gene, 23322 Neighboring gene predicted gene, 25797 Neighboring gene SH3-binding domain glutamic acid-rich protein like Neighboring gene upstream transcription factor 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC103386

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables nucleosomal DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chromatin IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    high mobility group nucleosome-binding domain-containing protein 5
    Names
    nucleosome binding protein 1
    nucleosome binding protein 45

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_016710.2NP_057919.2  high mobility group nucleosome-binding domain-containing protein 5

      See identical proteins and their annotated locations for NP_057919.2

      Status: VALIDATED

      Source sequence(s)
      AK146755, BY279928, BY387611
      Consensus CDS
      CCDS41101.1
      UniProtKB/Swiss-Prot
      O88832, Q3V272, Q8VC71, Q9CUW1, Q9JL35
      Related
      ENSMUSP00000033597.9, ENSMUST00000033597.9
      Conserved Domains (1) summary
      pfam01101
      Location:293
      HMG14_17; HMG14 and HMG17

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      108048143..108056986 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)