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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001007220.4 → NP_001007221.1 disintegrin and metalloproteinase domain-containing protein 22 isoform a precursor
See identical proteins and their annotated locations for NP_001007221.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1, also known as alpha or A04) encodes isoform a. This isoform (a) may undergo protein processing similar to isoform 5.
- Source sequence(s)
-
AC140364, AC152165, AC156022
- Consensus CDS
-
CCDS19080.1
- UniProtKB/TrEMBL
-
A4FUT9
- Related
- ENSMUSP00000049120.8, ENSMUST00000046838.14
- Conserved Domains (5) summary
-
- smart00608
Location:528 → 669
- ACR; ADAM Cysteine-Rich Domain
- cd04269
Location:237 → 434
- ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
- pfam00200
Location:451 → 525
- Disintegrin; Disintegrin
- pfam01421
Location:237 → 436
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:73 → 185
- Pep_M12B_propep; Reprolysin family propeptide
-
NM_001007221.4 → NP_001007222.1 disintegrin and metalloproteinase domain-containing protein 22 isoform b precursor
See identical proteins and their annotated locations for NP_001007222.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2, also known as beta or A05) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (b) is shorter than isoform a. This isoform (b) may undergo protein processing similar to isoform 5.
- Source sequence(s)
-
AC140364, AC152165, AC156022
- UniProtKB/TrEMBL
-
A4FUT9
- Conserved Domains (5) summary
-
- smart00608
Location:528 → 669
- ACR; ADAM Cysteine-Rich Domain
- cd04269
Location:237 → 434
- ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
- pfam00200
Location:451 → 525
- Disintegrin; Disintegrin
- pfam01421
Location:237 → 436
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:73 → 185
- Pep_M12B_propep; Reprolysin family propeptide
-
NM_001098225.3 → NP_001091695.1 disintegrin and metalloproteinase domain-containing protein 22 isoform c precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (3, also known as G03) contains multiple differences in the 3' coding region and differs in the 3' UTR compared variant 1. The encoded isoform (c) has a distinct C-terminus and is longer than isoform a. This isoform (c) may undergo protein processing similar to isoform 5.
- Source sequence(s)
-
AC140364, AC152165, AC156022
- Consensus CDS
-
CCDS51411.1
- UniProtKB/TrEMBL
-
A4FUT9
- Related
- ENSMUSP00000055000.8, ENSMUST00000050166.14
- Conserved Domains (5) summary
-
- smart00608
Location:528 → 669
- ACR; ADAM Cysteine-Rich Domain
- cd04269
Location:237 → 434
- ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
- pfam00200
Location:451 → 525
- Disintegrin; Disintegrin
- pfam01421
Location:237 → 436
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:73 → 185
- Pep_M12B_propep; Reprolysin family propeptide
-
NM_001310439.2 → NP_001297368.1 disintegrin and metalloproteinase domain-containing protein 22 isoform 4 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (4, also known as G07) contains multiple differences in the 3' coding region and differs in the 3' UTR compared variant 1. The encoded isoform (c) has a distinct C-terminus and is longer than isoform a. This isoform (4) may undergo protein processing similar to isoform 5.
- Source sequence(s)
-
AC140364, AC152165, AC156022
- Consensus CDS
-
CCDS80205.1
- UniProtKB/TrEMBL
-
A4FUT9
- Related
- ENSMUSP00000111046.3, ENSMUST00000115388.9
- Conserved Domains (5) summary
-
- smart00608
Location:528 → 669
- ACR; ADAM Cysteine-Rich Domain
- cd04269
Location:237 → 434
- ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
- pfam00200
Location:451 → 525
- Disintegrin; Disintegrin
- pfam01421
Location:237 → 436
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:73 → 185
- Pep_M12B_propep; Reprolysin family propeptide
-
NM_001310440.2 → NP_001297369.1 disintegrin and metalloproteinase domain-containing protein 22 isoform 5 preproprotein
See identical proteins and their annotated locations for NP_001297369.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (5, also known as G01) differs in the 3' coding region and 3' UTR compared to variant 1. The encoded isoform (c) has a longer C-terminus than isoform a.
- Source sequence(s)
-
AC140364, AC152165, AC156022
- Consensus CDS
-
CCDS80207.1
- UniProtKB/Swiss-Prot
- Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5, Q9R1V6
- UniProtKB/TrEMBL
- A4FUT9, D6QSS8
- Related
- ENSMUSP00000086139.5, ENSMUST00000088761.11
- Conserved Domains (5) summary
-
- smart00608
Location:528 → 669
- ACR; ADAM Cysteine-Rich Domain
- cd04269
Location:237 → 434
- ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
- pfam00200
Location:451 → 525
- Disintegrin; Disintegrin
- pfam01421
Location:237 → 436
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:73 → 185
- Pep_M12B_propep; Reprolysin family propeptide
-
NM_001418085.1 → NP_001405014.1 disintegrin and metalloproteinase domain-containing protein 22 isoform 6 precursor
Status: REVIEWED
- Source sequence(s)
-
AC140364, AC152165, AC156022
- UniProtKB/TrEMBL
-
A4FUT9
-
NM_001418086.1 → NP_001405015.1 disintegrin and metalloproteinase domain-containing protein 22 isoform 7 precursor
Status: REVIEWED
- Source sequence(s)
-
AC140364, AC152165, AC156022
- UniProtKB/TrEMBL
-
A4FUT9
-
NM_001418087.1 → NP_001405016.1 disintegrin and metalloproteinase domain-containing protein 22 isoform 8 precursor
Status: REVIEWED
- Source sequence(s)
-
AC140364, AC152165, AC156022
- UniProtKB/TrEMBL
-
D3YUQ0
- Related
- ENSMUSP00000111043.2, ENSMUST00000115385.2
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCm39 C57BL/6J
Genomic
-
NC_000071.7 Reference GRCm39 C57BL/6J
- Range
-
8122353..8418312 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_006503534.5 → XP_006503597.1 disintegrin and metalloproteinase domain-containing protein 22 isoform X7
- UniProtKB/TrEMBL
-
A4FUT9
- Conserved Domains (5) summary
-
- smart00608
Location:528 → 669
- ACR; ADAM Cysteine-Rich Domain
- pfam07974
Location:677 → 709
- EGF_2; EGF-like domain
- pfam00200
Location:451 → 524
- Disintegrin
- pfam01421
Location:237 → 436
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:48 → 186
- Pep_M12B_propep; Reprolysin family propeptide
-
XM_006503540.5 → XP_006503603.1 disintegrin and metalloproteinase domain-containing protein 22 isoform X12
- UniProtKB/TrEMBL
- A4FUT9, D3YUP9
- Related
- ENSMUSP00000111044.2, ENSMUST00000115386.8
- Conserved Domains (5) summary
-
- smart00608
Location:528 → 669
- ACR; ADAM Cysteine-Rich Domain
- pfam07974
Location:677 → 709
- EGF_2; EGF-like domain
- pfam00200
Location:451 → 524
- Disintegrin
- pfam01421
Location:237 → 436
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:48 → 186
- Pep_M12B_propep; Reprolysin family propeptide
-
XM_006503536.5 → XP_006503599.1 disintegrin and metalloproteinase domain-containing protein 22 isoform X10
- UniProtKB/TrEMBL
-
A4FUT9
- Conserved Domains (5) summary
-
- smart00608
Location:528 → 669
- ACR; ADAM Cysteine-Rich Domain
- pfam07974
Location:677 → 709
- EGF_2; EGF-like domain
- pfam00200
Location:451 → 524
- Disintegrin
- pfam01421
Location:237 → 436
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:48 → 186
- Pep_M12B_propep; Reprolysin family propeptide
-
XM_006503537.5 → XP_006503600.1 disintegrin and metalloproteinase domain-containing protein 22 isoform X11
- UniProtKB/TrEMBL
-
A4FUT9
- Conserved Domains (5) summary
-
- smart00608
Location:528 → 669
- ACR; ADAM Cysteine-Rich Domain
- pfam07974
Location:677 → 709
- EGF_2; EGF-like domain
- pfam00200
Location:451 → 524
- Disintegrin
- pfam01421
Location:237 → 436
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:48 → 186
- Pep_M12B_propep; Reprolysin family propeptide
-
XM_006503532.5 → XP_006503595.1 disintegrin and metalloproteinase domain-containing protein 22 isoform X5
- UniProtKB/TrEMBL
-
A4FUT9
- Conserved Domains (5) summary
-
- smart00608
Location:528 → 669
- ACR; ADAM Cysteine-Rich Domain
- pfam07974
Location:677 → 709
- EGF_2; EGF-like domain
- pfam00200
Location:451 → 524
- Disintegrin
- pfam01421
Location:237 → 436
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:48 → 186
- Pep_M12B_propep; Reprolysin family propeptide
-
XM_006503533.5 → XP_006503596.1 disintegrin and metalloproteinase domain-containing protein 22 isoform X6
- UniProtKB/TrEMBL
-
A4FUT9
- Conserved Domains (5) summary
-
- smart00608
Location:528 → 669
- ACR; ADAM Cysteine-Rich Domain
- pfam07974
Location:677 → 709
- EGF_2; EGF-like domain
- pfam00200
Location:451 → 524
- Disintegrin
- pfam01421
Location:237 → 436
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:48 → 186
- Pep_M12B_propep; Reprolysin family propeptide
-
XM_006503530.5 → XP_006503593.1 disintegrin and metalloproteinase domain-containing protein 22 isoform X3
- UniProtKB/TrEMBL
-
A4FUT9
- Conserved Domains (5) summary
-
- smart00608
Location:528 → 669
- ACR; ADAM Cysteine-Rich Domain
- pfam07974
Location:677 → 709
- EGF_2; EGF-like domain
- pfam00200
Location:451 → 524
- Disintegrin
- pfam01421
Location:237 → 436
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:48 → 186
- Pep_M12B_propep; Reprolysin family propeptide
-
XM_006503528.5 → XP_006503591.1 disintegrin and metalloproteinase domain-containing protein 22 isoform X1
- UniProtKB/TrEMBL
-
A4FUT9
- Conserved Domains (5) summary
-
- smart00608
Location:528 → 669
- ACR; ADAM Cysteine-Rich Domain
- pfam07974
Location:677 → 709
- EGF_2; EGF-like domain
- pfam00200
Location:451 → 524
- Disintegrin
- pfam01421
Location:237 → 436
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:48 → 186
- Pep_M12B_propep; Reprolysin family propeptide
-
XM_006503535.5 → XP_006503598.1 disintegrin and metalloproteinase domain-containing protein 22 isoform X8
- UniProtKB/TrEMBL
-
A4FUT9
- Conserved Domains (4) summary
-
- smart00608
Location:528 → 669
- ACR; ADAM Cysteine-Rich Domain
- pfam00200
Location:451 → 524
- Disintegrin
- pfam01421
Location:237 → 436
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:48 → 186
- Pep_M12B_propep; Reprolysin family propeptide
-
XM_006503531.5 → XP_006503594.1 disintegrin and metalloproteinase domain-containing protein 22 isoform X4
- UniProtKB/TrEMBL
-
A4FUT9
- Conserved Domains (5) summary
-
- smart00608
Location:528 → 669
- ACR; ADAM Cysteine-Rich Domain
- pfam07974
Location:677 → 709
- EGF_2; EGF-like domain
- pfam00200
Location:451 → 524
- Disintegrin
- pfam01421
Location:237 → 436
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:48 → 186
- Pep_M12B_propep; Reprolysin family propeptide
-
XM_006503529.5 → XP_006503592.1 disintegrin and metalloproteinase domain-containing protein 22 isoform X2
- UniProtKB/TrEMBL
-
A4FUT9
- Conserved Domains (5) summary
-
- smart00608
Location:528 → 669
- ACR; ADAM Cysteine-Rich Domain
- pfam07974
Location:677 → 709
- EGF_2; EGF-like domain
- pfam00200
Location:451 → 524
- Disintegrin
- pfam01421
Location:237 → 436
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:48 → 186
- Pep_M12B_propep; Reprolysin family propeptide
-
XM_030254064.2 → XP_030109924.1 disintegrin and metalloproteinase domain-containing protein 22 isoform X13
- UniProtKB/TrEMBL
-
A4FUT9
- Conserved Domains (4) summary
-
- smart00608
Location:528 → 669
- ACR; ADAM Cysteine-Rich Domain
- pfam00200
Location:451 → 524
- Disintegrin
- pfam01421
Location:237 → 436
- Reprolysin; Reprolysin (M12B) family zinc metalloprotease
- pfam01562
Location:48 → 186
- Pep_M12B_propep; Reprolysin family propeptide
RNA
-
XR_376691.4 RNA Sequence