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    Lcn12 lipocalin 12 [ Mus musculus (house mouse) ]

    Gene ID: 77701, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lcn12provided by MGI
    Official Full Name
    lipocalin 12provided by MGI
    Primary source
    MGI:MGI:1924951
    See related
    Ensembl:ENSMUSG00000026943 AllianceGenome:MGI:1924951
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9230102M18Rik
    Summary
    Predicted to enable retinoic acid binding activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human LCN12 (lipocalin 12). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward genital fat pad adult (RPKM 71.5) See more
    Orthologs
    human all
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    Genomic context

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    See Lcn12 in Genome Data Viewer
    Location:
    2 A3; 2 17.3 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (25380857..25384073, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (25490845..25494061, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene prostaglandin D2 synthase (brain) Neighboring gene predicted gene, 35287 Neighboring gene STARR-positive B cell enhancer ABC_E9193 Neighboring gene F-box and WD-40 domain protein 5 Neighboring gene complement component 8, gamma polypeptide Neighboring gene TNF receptor-associated factor 2 Neighboring gene cytochrome c oxidase subunit 7A2, mitochondrial pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Molecular evolution of epididymal lipocalin genes localized on mouse chromosome 2. Suzuki K, et al. Gene, 2004 Sep 15. PMID 15363845
    2. Update on the human and mouse lipocalin (LCN) gene family, including evidence the mouse Mup cluster is result of an "evolutionary bloom". Charkoftaki G, et al. Hum Genomics, 2019 Feb 19. PMID 30782214, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC130532

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables retinoic acid binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables retinoic acid binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    epididymal-specific lipocalin-12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029958.1 → NP_084234.1  epididymal-specific lipocalin-12 precursor

      See identical proteins and their annotated locations for NP_084234.1

      Status: VALIDATED

      Source sequence(s)
      AY299493
      Consensus CDS
      CCDS15776.1
      UniProtKB/Swiss-Prot
      Q6JVL5
      UniProtKB/TrEMBL
      Q2TA58, Q9D265
      Related
      ENSMUSP00000028312.7, ENSMUST00000028312.13
      Conserved Domains (1) summary
      pfam00061
      Location:40 → 185
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      25380857..25384073 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011239211.1 → XP_011237513.1  epididymal-specific lipocalin-12 isoform X1

      Conserved Domains (1) summary
      cd19458
      Location:29 → 185
      lipocalin_12; Lipocalin 12

    2. XM_017319337.1 → XP_017174826.1  epididymal-specific lipocalin-12 isoform X2

      Conserved Domains (1) summary
      cl10502
      Location:2 → 149
      lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6JVL5.1 GenPept UniProtKB/Swiss-Prot:Q6JVL5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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