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    Fbxl6 F-box and leucine-rich repeat protein 6 [ Mus musculus (house mouse) ]

    Gene ID: 30840, updated on 9-Dec-2024

    Summary

    Official Symbol
    Fbxl6provided by MGI
    Official Full Name
    F-box and leucine-rich repeat protein 6provided by MGI
    Primary source
    MGI:MGI:1354705
    See related
    Ensembl:ENSMUSG00000022559 AllianceGenome:MGI:1354705
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fbl6
    Summary
    Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human FBXL6 (F-box and leucine rich repeat protein 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 75.4), adrenal adult (RPKM 61.6) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Fbxl6 in Genome Data Viewer
    Location:
    15 D3; 15 36.04 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (76419923..76422946, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (76535723..76538746, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46533 Neighboring gene transmembrane protein 249 Neighboring gene STARR-positive B cell enhancer ABC_E3144 Neighboring gene solute carrier protein 52, member 2 Neighboring gene predicted gene, 35739

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General protein information

    Preferred Names
    F-box/LRR-repeat protein 6
    Names
    F-box protein FBL6
    F-box protein containing leucine repeats 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013909.2NP_038937.2  F-box/LRR-repeat protein 6

      See identical proteins and their annotated locations for NP_038937.2

      Status: VALIDATED

      Source sequence(s)
      AF176522, AK040458, BC054377
      Consensus CDS
      CCDS49653.1
      UniProtKB/Swiss-Prot
      Q9JJD7, Q9QXW0
      Related
      ENSMUSP00000023219.8, ENSMUST00000023219.9
      Conserved Domains (3) summary
      cd09293
      Location:171390
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:188213
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:105155
      F-box-like; F-box-like

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      76419923..76422946 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)