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    cyoE heme O synthase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945073, updated on 17-Dec-2024

    Summary

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    Official Symbol
    cyoE
    Official Full Name
    heme O synthase
    Primary source
    ECOCYC:EG10182
    Locus tag
    b0428
    See related
    ASAP:ABE-0001484
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0422
    Summary
    The CyoE protein, heme O synthase, catalyzes the synthesis of heme O, which is essential for the catalytic fuctions of the cytochrome bo oxidase complex . [More information is available at EcoCyc: EG10182].
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    Genomic context

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    Sequence:
    NC_000913.3 (446815..447705, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene nucleotide binding protein YajQ Neighboring gene putative transport protein YajR Neighboring gene cytochrome bo3 subunit 4 Neighboring gene cytochrome bo3 subunit 3 Neighboring gene cytochrome bo3 subunit 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Biosynthesis and functional role of haem O and haem A. Mogi T, et al. Mol Microbiol, 1994 Nov. PMID 7885224
    2. In vitro heme O synthesis by the cyoE gene product from Escherichia coli. Saiki K, et al. J Biol Chem, 1993 Dec 15. PMID 8253713
    3. Identification of the functional domains in heme O synthase. Site-directed mutagenesis studies on the cyoE gene of the cytochrome bo operon in Escherichia coli. Saiki K, et al. J Biol Chem, 1993 Dec 25. PMID 8262927
    4. Effects of replacement of low-spin haem b by haem O on Escherichia coli cytochromes bo and bd quinol oxidases. Mogi T. J Biochem, 2009 May. PMID 19174546
    5. Transcriptional regulation of the cytochrome b562-o complex in Escherichia coli. Gene expression and molecular characterization of the promoter. Minagawa J, et al. J Biol Chem, 1990 Jul 5. PMID 2162837

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables protoheme IX farnesyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protoheme IX farnesyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protoheme IX farnesyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in heme O biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within heme O biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in heme O biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in heme biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    heme O synthase
    NP_414962.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      446815..447705 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414962.1 heme O synthase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414962.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A836NFX9, A0A8E0KWV1, A0A8S7QXC7, A0A8S7S3Q4, A0A979GCN8, A0AAN3V2A1, A0AAN4SZM0, A0AAV3HEZ8, A0AAV3IC96, W1F2Z5
      Conserved Domains (1) summary
      PRK13362
      Location:1 → 296
      PRK13362; protoheme IX farnesyltransferase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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