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    lpxT lipid A-core phosphotransferase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946693, updated on 3-Dec-2024

    Summary

    Official Symbol
    lpxT
    Official Full Name
    lipid A-core phosphotransferase
    Primary source
    ECOCYC:G7146
    Locus tag
    b2174
    See related
    ASAP:ABE-0007196
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2168; yeiU
    Summary
    One third of the lipid A pool is lipid A 1-diphosphate formed by a periplasmic domain of LpxT (Touze, 2008). ybjG, pgpB, and lpxT are paralogs. [More information is available at EcoGene: EG14075]. LpxT is responsible for transfer of a phosphate group from undecaprenyl-pyrophosphate to the position 1 phosphate of approximately one-third of lipid A molecules to create lipid A 1-diphosphate. [More information is available at EcoCyc: G7146].
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    Genomic context

    Sequence:
    NC_000913.3 (2268854..2269567)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative oxidoreductase YeiQ Neighboring gene zinc-binding GTPase YeiR Neighboring gene peptidoglycan endopeptidase/peptidoglycan L,D-carboxypeptidase Neighboring gene putative c-di-GMP phosphodiesterase PdeN

    Bibliography

    General protein information

    Preferred Names
    lipid A-core phosphotransferase
    NP_416679.4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2268854..2269567
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416679.4 lipid A-core phosphotransferase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416679.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376SBR1, A0A418GGF0, A0A8S7HXC4
      Conserved Domains (1) summary
      smart00014
      Location:98210
      acidPPc; Acid phosphatase homologues