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    rpsO 30S ribosomal subunit protein S15 [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947686, updated on 3-Dec-2024

    Summary

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    Official Symbol
    rpsO
    Official Full Name
    30S ribosomal subunit protein S15
    Primary source
    ECOCYC:EG10914
    Locus tag
    b3165
    See related
    ASAP:ABE-0010401
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3154; secC
    Summary
    The S15 protein is a component of the 30S subunit of the ribosome and also functions in the post-transcriptional regulation of its own expression. [More information is available at EcoCyc: EG10914].
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    Genomic context

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    Sequence:
    NC_000913.3 (3311415..3311684, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene polynucleotide phosphorylase Neighboring gene ncRNA Neighboring gene tRNA pseudouridine(55) synthase Neighboring gene 30S ribosome binding factor Neighboring gene translation initiation factor IF-2beta'

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification in a pseudoknot of a U.G motif essential for the regulation of the expression of ribosomal protein S15. Bénard L, et al. Proc Natl Acad Sci U S A, 1998 Mar 3. PMID 9482926, Free PMC Article
    2. More than one way to skin a cat: translational autoregulation by ribosomal protein S15. Springer M, et al. Nat Struct Biol, 2003 Jun. PMID 12768202
    3. Specific recognition of rpsO mRNA and 16S rRNA by Escherichia coli ribosomal protein S15 relies on both mimicry and site differentiation. Mathy N, et al. Mol Microbiol, 2004 May. PMID 15101974, Free PMC Article
    4. Effects of site-directed mutations in the central domain of 16 S ribosomal RNA upon ribosomal protein binding, RNA processing and 30 S subunit assembly. Stark MJ, et al. J Mol Biol, 1984 Sep 15. PMID 6208367
    5. The product of gene secC is involved in the synthesis of exported proteins in E. coli. Ferro-Novick S, et al. Cell, 1984 Aug. PMID 6088066

    See all (80) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Uncovering a delicate balance between endonuclease RNase III and ribosomal protein S15 in E. coli ribosome assembly.
      Title: Uncovering a delicate balance between endonuclease RNase III and ribosomal protein S15 in E. coli ribosome assembly.
    2. In the stalled state, the folded mRNA prevents the start codon from reaching the peptidyl-tRNA (P) site inside the ribosome. Upon S15/repressor release, the mRNA unfolds and moves into the mRNA channel allowing translation initiation.
      Title: Structured mRNAs regulate translation initiation by binding to the platform of the ribosome.
    3. N-terminus verified by Edman degradation on mature peptide
      Title: Primary structure of the 16S rRNA binding protein S15 from Escherichia coli ribosomes.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables rRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables small ribosomal subunit rRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosomal small subunit assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within translation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic small ribosomal subunit IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    30S ribosomal subunit protein S15

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3311415..3311684 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417634.1 30S ribosomal subunit protein S15 [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417634.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A090AY10
      Conserved Domains (1) summary
      PRK05626
      Location:1 → 89
      rpsO; 30S ribosomal protein S15; Reviewed
    Nucleotide Protein
    Heading Accession and Version

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