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    ugpB sn-glycerol 3-phosphate ABC transporter periplasmic binding protein [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947962, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ugpB
    Official Full Name
    sn-glycerol 3-phosphate ABC transporter periplasmic binding protein
    Primary source
    ECOCYC:EG11047
    Locus tag
    b3453
    See related
    ASAP:ABE-0011274
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3437; psiB; psiC
    Summary
    Pho regulon. [More information is available at EcoGene: EG11047]. The UgpABCE glycerol-3-phosphate uptake system is a member of the ATP-Binding Cassette (ABC) Superfamily . [More information is available at EcoCyc: EG11047].
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    Genomic context

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    Sequence:
    NC_000913.3 (3591009..3592325, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene glycerophosphodiester phosphodiesterase UgpQ Neighboring gene sn-glycerol 3-phosphate ABC transporter ATP binding subunit Neighboring gene sn-glycerol 3-phosphate ABC transporter membrane subunit UgpE Neighboring gene sn-glycerol 3-phosphate ABC transporter membrane subunit UgpA Neighboring gene branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF Neighboring gene branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG Neighboring gene branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A metabolite binding protein moonlights as a bile-responsive chaperone. Lee C, et al. EMBO J, 2020 Oct 15. PMID 32882062, Free PMC Article
    2. Purification and properties of the sn-glycerol 3-phosphate-binding protein of Escherichia coli. Argast M, et al. J Biol Chem, 1979 Nov 10. PMID 387762
    3. Determinants of substrate specificity and biochemical properties of the sn-glycerol-3-phosphate ATP binding cassette transporter (UgpB-AEC2 ) of Escherichia coli. Wuttge S, et al. Mol Microbiol, 2012 Nov. PMID 23013274
    4. Effects of halo analogs of glycerol 3-phosphate and dihydroxyacetone phosphate upon Escherichia coli. Mildener B, et al. Antimicrob Agents Chemother, 1981 Apr. PMID 7018394, Free PMC Article
    5. Characterization of the ugp region containing the genes for the phoB dependent sn-glycerol-3-phosphate transport system of Escherichia coli. Schweizer H, et al. Mol Gen Genet, 1984. PMID 6392822

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A metabolite binding protein moonlights as a bile-responsive chaperone.
      Title: A metabolite binding protein moonlights as a bile-responsive chaperone.
    2. Mutations in the ugpBAECQ operon (Ugp)eliminated the ability of phoA-deleted E. coli to utilize glycerol-2-phosphate (G2P)suggesting that G2P is a previously unrecognized substrate for the binding protein-dependent Ugp transporter.
      Title: Uptake of glycerol-2-phosphate via the ugp-encoded transporter in Escherichia coli K-12.
    3. N-terminus verified by Edman degradation on mature peptide
      Title: Nucleotide sequence of the ugp genes of Escherichia coli K-12: homology to the maltose system.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    acts_upstream_of_or_within glycerol-3-phosphate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in glycerol-3-phosphate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within glycerol-3-phosphate transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within glycerophosphodiester transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of glycerol-3-phosphate-transporting ATPase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in outer membrane-bounded periplasmic space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in outer membrane-bounded periplasmic space IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in periplasmic space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sn-glycerol 3-phosphate ABC transporter periplasmic binding protein
    NP_417910.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3591009..3592325 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417910.1 sn-glycerol 3-phosphate ABC transporter periplasmic binding protein [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417910.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6L7C8I2
      Conserved Domains (1) summary
      PRK10974
      Location:18 → 437
      PRK10974; sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB
    Nucleotide Protein
    Heading Accession and Version

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