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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001195415.2 → NP_001182344.1 serine/threonine-protein kinase DCLK1 isoform 2
See identical proteins and their annotated locations for NP_001182344.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2, also known as DCLK-short-B, DCK-beta1 or KIAA0369-BS) is produced from the 3' promoter. It lacks several 5' exons but has an alternate 5' exon, as compared to variant 1. The resulting isoform (2) has a shorter and different N-terminus, and lacks doublecortin domains, as compared to isoform 1.
- Source sequence(s)
-
AK295777, AL139083, AL157760
- Consensus CDS
-
CCDS73561.1
- UniProtKB/TrEMBL
-
B7Z5K4
- Related
- ENSP00000484452.1, ENST00000615680.5
- Conserved Domains (1) summary
-
- cd14183
Location:76 → 343
- STKc_DCKL1; Catalytic domain of the Serine/Threonine Kinase, Doublecortin-like kinase 1 (also called Doublecortin-like and CAM kinase-like 1)
-
NM_001195416.2 → NP_001182345.1 serine/threonine-protein kinase DCLK1 isoform 3
See identical proteins and their annotated locations for NP_001182345.1
Status: REVIEWED
- Description
- Transcript Variant: This variant [3, also known as DCLK-short-A, DCK-beta2, KIAA0369-BL or cpg16 (candidate plasticity gene 16)] is produced from the 3' promoter. It lacks several 5' exons but has an alternate 5' exon, and lacks a coding exon in the 3' region that results in a frame-shift, as compared to variant 1. The resulting isoform (3) has a shorter and different N-terminus and a longer and distinct C-terminus, and lacks doublecortin domains, as compared to isoform 1.
- Source sequence(s)
-
AK299059, AK311195, AL139083, AL157760, BC152456
- Consensus CDS
-
CCDS55895.1
- UniProtKB/TrEMBL
-
B7Z5K4
- Related
- ENSP00000369223.1, ENST00000379893.5
- Conserved Domains (1) summary
-
- cd14183
Location:76 → 343
- STKc_DCKL1; Catalytic domain of the Serine/Threonine Kinase, Doublecortin-like kinase 1 (also called Doublecortin-like and CAM kinase-like 1)
-
NM_001195430.2 → NP_001182359.1 serine/threonine-protein kinase DCLK1 isoform 4
See identical proteins and their annotated locations for NP_001182359.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) is produced from the 3' promoter. It shares only one exon with variant 1, and encodes a 56 aa long isoform [4, also known as ania-4, or CARP (CaMK-related peptide)], which mainly consists of the serine/proline-rich domain.
- Source sequence(s)
-
AL157760, BM682165
- UniProtKB/TrEMBL
-
A0A9L9PXT2
- Related
- ENSP00000516676.1, ENST00000460982.1
-
NM_001330071.2 → NP_001317000.1 serine/threonine-protein kinase DCLK1 isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks an alternate exon in the 3' coding region, resulting in a frameshift compared to variant 1. Both variants 5 and 6 encode the same isoform (5), which is longer and has a distinct C-terminus compared to isoform 1.
- Source sequence(s)
-
AK295777, AL139083, AL157760, AL160392, BC152456, BM679448, DB453639, DC350316, HY138649
- Consensus CDS
-
CCDS81762.1
- UniProtKB/Swiss-Prot
- B7Z3E9, O15075, Q5VZY8, Q5VZZ0, Q5VZZ1
- UniProtKB/TrEMBL
-
B7Z2T7
- Related
- ENSP00000353846.3, ENST00000360631.8
- Conserved Domains (3) summary
-
- cd14183
Location:383 → 650
- STKc_DCKL1; Catalytic domain of the Serine/Threonine Kinase, Doublecortin-like kinase 1 (also called Doublecortin-like and CAM kinase-like 1)
- cd17069
Location:182 → 265
- DCX2; Dublecortin-like domain 2
- cd17140
Location:55 → 143
- DCX1_DCLK1; Dublecortin-like domain 1 found in doublecortin-like kinase 1 (DCLK1)
-
NM_001330072.2 → NP_001317001.1 serine/threonine-protein kinase DCLK1 isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) differs in the 5' UTR and lacks an alternate exon in the 3' coding region, resulting in a frameshift compared to variant 1. Both variants 5 and 6 encode the same isoform (5), which is longer and has a distinct C-terminus compared to isoform 1.
- Source sequence(s)
-
AK295777, AL139083, AL157760, BC152456, BM679448, DA154341, DC350316
- Consensus CDS
-
CCDS81762.1
- UniProtKB/Swiss-Prot
- B7Z3E9, O15075, Q5VZY8, Q5VZZ0, Q5VZZ1
- UniProtKB/TrEMBL
-
B7Z2T7
- Conserved Domains (3) summary
-
- cd14183
Location:383 → 650
- STKc_DCKL1; Catalytic domain of the Serine/Threonine Kinase, Doublecortin-like kinase 1 (also called Doublecortin-like and CAM kinase-like 1)
- cd17069
Location:182 → 265
- DCX2; Dublecortin-like domain 2
- cd17140
Location:55 → 143
- DCX1_DCLK1; Dublecortin-like domain 1 found in doublecortin-like kinase 1 (DCLK1)
-
NM_004734.5 → NP_004725.1 serine/threonine-protein kinase DCLK1 isoform 1
See identical proteins and their annotated locations for NP_004725.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1, also known as DCLK-long-B, DCK-alpha1 or KIAA0369AS) is produced from the 5' promoter. It encodes the isoform 1, which includes two doublecortin domains, a serine/proline-rich domain and a protein kinase domain.
- Source sequence(s)
-
AK295777, AL139083, AL157760, AL160392, BC152456
- Consensus CDS
-
CCDS9354.1
- UniProtKB/TrEMBL
-
B7Z2T7
- Related
- ENSP00000255448.4, ENST00000255448.8
- Conserved Domains (3) summary
-
- cd14183
Location:383 → 650
- STKc_DCKL1; Catalytic domain of the Serine/Threonine Kinase, Doublecortin-like kinase 1 (also called Doublecortin-like and CAM kinase-like 1)
- cd17069
Location:182 → 265
- DCX2; Dublecortin-like domain 2
- cd17140
Location:55 → 143
- DCX1_DCLK1; Dublecortin-like domain 1 found in doublecortin-like kinase 1 (DCLK1)
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000013.11 Reference GRCh38.p14 Primary Assembly
- Range
-
35768652..36131939 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017020847.2 → XP_016876336.1 serine/threonine-protein kinase DCLK1 isoform X1
- UniProtKB/TrEMBL
-
B7Z2T7
- Conserved Domains (3) summary
-
- cd14183
Location:383 → 650
- STKc_DCKL1; Catalytic domain of the Serine/Threonine Kinase, Doublecortin-like kinase 1 (also called Doublecortin-like and CAM kinase-like 1)
- cd17069
Location:182 → 265
- DCX2; Dublecortin-like domain 2
- cd17140
Location:55 → 143
- DCX1_DCLK1; Dublecortin-like domain 1 found in doublecortin-like kinase 1 (DCLK1)
-
XM_047430767.1 → XP_047286723.1 serine/threonine-protein kinase DCLK1 isoform X2
- UniProtKB/TrEMBL
-
Q5VZY9
-
XM_017020848.2 → XP_016876337.1 serine/threonine-protein kinase DCLK1 isoform X2
- UniProtKB/TrEMBL
-
Q5VZY9
- Related
- ENSP00000369222.4, ENST00000379892.4
- Conserved Domains (2) summary
-
- cd17069
Location:182 → 265
- DCX2; Dublecortin-like domain 2
- cd17140
Location:55 → 143
- DCX1_DCLK1; Dublecortin-like domain 1 found in doublecortin-like kinase 1 (DCLK1)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060937.1 Alternate T2T-CHM13v2.0
- Range
-
34986929..35351445 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054375170.1 → XP_054231145.1 serine/threonine-protein kinase DCLK1 isoform X1
- UniProtKB/TrEMBL
-
B7Z2T7
-
XM_054375172.1 → XP_054231147.1 serine/threonine-protein kinase DCLK1 isoform X2
- UniProtKB/TrEMBL
-
Q5VZY9
-
XM_054375171.1 → XP_054231146.1 serine/threonine-protein kinase DCLK1 isoform X2
- UniProtKB/TrEMBL
-
Q5VZY9