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    ltaE low-specificity L-threonine aldolase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944955, updated on 3-Dec-2024

    Summary

    Official Symbol
    ltaE
    Official Full Name
    low-specificity L-threonine aldolase
    Primary source
    ECOCYC:G6455
    Locus tag
    b0870
    See related
    ASAP:ABE-0002954
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0861; ltaA; ybjU
    Summary
    The L-threonine aldolase encoded by the ltaA gene is of the low-specificity type; it can act on both L-threonine and L-allo-threonine as well as L-threo-phenylserine and L-erythro-phenylserine, but does not utilize the D isomers. [More information is available at EcoCyc: G6455].
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    Genomic context

    Sequence:
    NC_000913.3 (908293..909294, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene N-acetylmuramoyl-L-alanine amidase D Neighboring gene putative epimerase YbjS Neighboring gene putative NAD(P)-binding protein YbjT Neighboring gene pyruvate oxidase Neighboring gene NADH oxidoreductase

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables L-allo-threonine aldolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables L-allo-threonine aldolase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables L-allo-threonine aldolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phenylserine aldolase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables pyridoxal phosphate binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in amino acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within glycine biosynthetic process EXP
    Inferred from Experiment
    more info
    PubMed 
    involved_in glycine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in threonine catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    low-specificity L-threonine aldolase
    NP_415391.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      908293..909294 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415391.1 low-specificity L-threonine aldolase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415391.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6N3AZF1
      Conserved Domains (1) summary
      PRK10534
      Location:1333
      PRK10534; L-threonine aldolase; Provisional