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    Unc119b unc-119 lipid binding chaperone B [ Mus musculus (house mouse) ]

    Gene ID: 106840, updated on 9-Dec-2024

    Summary

    Official Symbol
    Unc119bprovided by MGI
    Official Full Name
    unc-119 lipid binding chaperone Bprovided by MGI
    Primary source
    MGI:MGI:2147162
    See related
    Ensembl:ENSMUSG00000046562 AllianceGenome:MGI:2147162
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable lipid binding activity. Predicted to be involved in cilium assembly; lipoprotein transport; and nervous system development. Predicted to be located in ciliary transition zone. Predicted to be active in cilium. Is expressed in several structures, including central nervous system; genitourinary system; gut; respiratory system; and sensory organ. Orthologous to human UNC119B (unc-119 lipid binding chaperone B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in kidney adult (RPKM 45.6), genital fat pad adult (RPKM 26.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Unc119b in Genome Data Viewer
    Location:
    5 F; 5 55.99 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (115260625..115273034, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (115122566..115134975, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L37, retrotransposed Neighboring gene acyl-Coenzyme A dehydrogenase, short chain Neighboring gene STARR-positive B cell enhancer ABC_E10342 Neighboring gene STARR-seq mESC enhancer starr_14100 Neighboring gene malectin Neighboring gene STARR-positive B cell enhancer ABC_E1058 Neighboring gene STARR-seq mESC enhancer starr_14105 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:115617496-115617679 Neighboring gene calcium binding protein 1 Neighboring gene STARR-seq mESC enhancer starr_14108 Neighboring gene predicted gene, 35515

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables lipid binding  
    enables lipid binding  
    enables lipid binding  
    Process Evidence Code Pubs
    involved_in cilium assembly  
    involved_in cilium assembly  
    involved_in cilium assembly  
    involved_in lipoprotein transport  
    involved_in lipoprotein transport  
    involved_in lipoprotein transport  
    involved_in nervous system development  
    Component Evidence Code Pubs
    located_in ciliary transition zone  
    located_in ciliary transition zone  
    is_active_in cilium  

    General protein information

    Preferred Names
    protein unc-119 homolog B
    Names
    unc-119 homolog B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175352.4NP_780561.1  protein unc-119 homolog B

      See identical proteins and their annotated locations for NP_780561.1

      Status: PROVISIONAL

      Source sequence(s)
      AC119205
      Consensus CDS
      CCDS19580.1
      UniProtKB/Swiss-Prot
      Q14BY8, Q8BRC4, Q8C4B4, Q922B4
      Related
      ENSMUSP00000055475.6, ENSMUST00000060798.6
      Conserved Domains (1) summary
      pfam05351
      Location:88247
      GMP_PDE_delta; GMP-PDE, delta subunit

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      115260625..115273034 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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