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    trpD anthranilate synthase subunit TrpD [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945109, updated on 3-Dec-2024

    Summary

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    Official Symbol
    trpD
    Official Full Name
    anthranilate synthase subunit TrpD
    Primary source
    ECOCYC:EG11027
    Locus tag
    b1263
    See related
    ASAP:ABE-0004241
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1257; trpGD
    Summary
    Anthranilate phosphoribosyl transferase (TrpD) catalyzes the second step in the pathway of tryptophan biosynthesis. [More information is available at EcoCyc: EG11027].
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    Genomic context

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    Sequence:
    NC_000913.3 (1319789..1321384, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene tryptophan synthase subunit alpha Neighboring gene tryptophan synthase subunit beta Neighboring gene fused indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase Neighboring gene anthranilate synthase subunit TrpE Neighboring gene trp operon leader peptide

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The anthranilate aggregate of Escherichia coli: kinetics of inhibition by tryptophan of phosphoribosyltransferase. Gonzalez JE, et al. Biochem Cell Biol, 1986 Jul. PMID 2428387
    2. Localization of two functions of the phosphoribosyl anthranilate transferase of Escherichia coli to distinct regions of the polypeptide chain. Jackson EN, et al. J Bacteriol, 1974 Feb. PMID 4590474, Free PMC Article
    3. Structural homology of the glutamine amidotransferase subunits of the anthranilate synthetases of Escherichia coli, Salmonella typhimurium and Serratia marcescens. Li SL, et al. Nature, 1974 Mar 1. PMID 4594441
    4. Nucleotide sequence of the trpD gene, encoding anthranilate synthetase component II of Escherichia coli. Horowitz H, et al. J Mol Biol, 1982 Apr 5. PMID 6283099
    5. Initiation in vivo at the internal trp p2 promoter of Escherichia coli. Horowitz H, et al. J Biol Chem, 1983 Jul 10. PMID 6305961

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on mature peptide
      Title: Structural homology of the glutamine amidotransferase subunits of the anthranilate synthetases of Escherichia coli, Salmonella typhimurium and Serratia marcescens.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    General protein information

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    Preferred Names
    anthranilate synthase subunit TrpD
    NP_415779.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1319789..1321384 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415779.1 anthranilate synthase subunit TrpD [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415779.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6N8QYT1
      Conserved Domains (1) summary
      PRK09522
      Location:1 → 531
      PRK09522; bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD
    Nucleotide Protein
    Heading Accession and Version

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