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    ecpA common pilus major subunit [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948759, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ecpA
    Official Full Name
    common pilus major subunit
    Primary source
    ECOCYC:G6164
    Locus tag
    b0293
    See related
    ASAP:ABE-0001009
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0292; matB; yagZ
    Summary
    SecB-dependent cleavage (Marani, 2006). [More information is available at EcoGene: EG13565]. MatB is a fimbrillin that is expressed in pathogenic Escherichia coli strains at low temperatures. [More information is available at EcoCyc: G6164].
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    Genomic context

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    Sequence:
    NC_000913.3 (310084..310671, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene fimbrial adhesin EcpD Neighboring gene putative fimbrial usher protein EcpC Neighboring gene putative fimbrial chaperone EcpB Neighboring gene DNA-binding transcriptional dual regulator MatA Neighboring gene uncharacterized protein YkgL

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Distribution of the Escherichia coli common pilus among diverse strains of human enterotoxigenic E. coli. Blackburn D, et al. J Clin Microbiol, 2009 Jun. PMID 19357209, Free PMC Article
    2. The Escherichia coli common pilus and the bundle-forming pilus act in concert during the formation of localized adherence by enteropathogenic E. coli. Saldaña Z, et al. J Bacteriol, 2009 Jun. PMID 19218393, Free PMC Article
    3. Commensal and pathogenic Escherichia coli use a common pilus adherence factor for epithelial cell colonization. Rendón MA, et al. Proc Natl Acad Sci U S A, 2007 Jun 19. PMID 17563352, Free PMC Article
    4. Fishing new proteins in the twilight zone of genomes: the test case of outer membrane proteins in Escherichia coli K12, Escherichia coli O157:H7, and other Gram-negative bacteria. Casadio R, et al. Protein Sci, 2003 Jun. PMID 12761386, Free PMC Article
    5. matB, a common fimbrillin gene of Escherichia coli, expressed in a genetically conserved, virulent clonal group. Pouttu R, et al. J Bacteriol, 2001 Aug. PMID 11466275, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on mature peptide
      Title: New Escherichia coli outer membrane proteins identified through prediction and experimental verification.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Component Evidence Code Pubs
    located_in pilus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    common pilus major subunit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      310084..310671 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414827.1 common pilus major subunit [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414827.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7CQI2
      Conserved Domains (1) summary
      pfam16449
      Location:26 → 193
      MatB; Fimbrillin MatB
    Nucleotide Protein
    Heading Accession and Version

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