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    yjeH L-methionine/branched chain amino acid exporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948656, updated on 3-Dec-2024

    Summary

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    Official Symbol
    yjeH
    Official Full Name
    L-methionine/branched chain amino acid exporter
    Primary source
    ECOCYC:G7833
    Locus tag
    b4141
    See related
    ASAP:ABE-0013559
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4135
    Summary
    A yjeH mutant of Salmonella has reduced ceftriaxone resistance and altered OM protein levels (Hu, 2007). [More information is available at EcoGene: EG12470]. YjeH is an uncharacterized member of the APC superfamily of amino acid transporters . [More information is available at EcoCyc: G7833].
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    Genomic context

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    Sequence:
    NC_000913.3 (4369156..4370412, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene aspartate ammonia-lyase Neighboring gene protein FxsA Neighboring gene cochaperonin GroES Neighboring gene chaperonin GroEL

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. YjeH Is a Novel Exporter of l-Methionine and Branched-Chain Amino Acids in Escherichia coli. Liu Q, et al. Appl Environ Microbiol, 2015 Nov. PMID 26319875, Free PMC Article
    2. A proteomic approach to study Salmonella enterica serovar Typhimurium putative transporter YjeH associated with ceftriaxone resistance. Hu WS, et al. Biochem Biophys Res Commun, 2007 Sep 28. PMID 17669360
    3. Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes. Burland V, et al. Nucleic Acids Res, 1995 Jun 25. PMID 7610040, Free PMC Article
    4. The amino acid/polyamine/organocation (APC) superfamily of transporters specific for amino acids, polyamines and organocations. Jack DL, et al. Microbiology (Reading), 2000 Aug. PMID 10931886
    5. Experimentally constrained topology models for 51,208 bacterial inner membrane proteins. Granseth E, et al. J Mol Biol, 2005 Sep 23. PMID 16120447

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables L-methionine secondary active transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables antiporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables neutral L-amino acid secondary active transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within L-leucine transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within L-valine transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cellular response to amino acid stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within isoleucine transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within methionine transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    L-methionine/branched chain amino acid exporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4369156..4370412 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418565.1 L-methionine/branched chain amino acid exporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418565.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7R6P5
      Conserved Domains (1) summary
      PRK11021
      Location:8 → 411
      PRK11021; putative transporter; Provisional
    Nucleotide Protein
    Heading Accession and Version

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