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    serC phosphoserine/phosphohydroxythreonine aminotransferase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945527, updated on 3-Dec-2024

    Summary

    Official Symbol
    serC
    Official Full Name
    phosphoserine/phosphohydroxythreonine aminotransferase
    Primary source
    ECOCYC:EG10946
    Locus tag
    b0907
    See related
    ASAP:ABE-0003093
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0898; pdxC; pdxF
    Summary
    The serC-encoded enzyme, phosphoserine/phosphohydroxythreonine aminotransferase, functions in the biosythesis of both serine and pyridoxine, by using different substrates . [More information is available at EcoCyc: EG10946].
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    Genomic context

    Sequence:
    NC_000913.3 (957653..958741)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene ribosomal protein S12 methylthiotransferase accessory factor YcaO Neighboring gene DUF421 domain-containing protein YcaP Neighboring gene 3-phosphoshikimate 1-carboxyvinyltransferase Neighboring gene periplasmic protease YcaL

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables O-phospho-L-serine:2-oxoglutarate aminotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables O-phospho-L-serine:2-oxoglutarate aminotransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables O-phospho-L-serine:2-oxoglutarate aminotransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables pyridoxal phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables pyridoxal phosphate binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transaminase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    phosphoserine/phosphohydroxythreonine aminotransferase
    NP_415427.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      957653..958741
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415427.1 phosphoserine/phosphohydroxythreonine aminotransferase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415427.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FLI0
      Conserved Domains (1) summary
      PRK05355
      Location:1362
      PRK05355; 3-phosphoserine/phosphohydroxythreonine transaminase