purT phosphoribosylglycinamide formyltransferase 2 [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Official Symbol: purT
Official Full Name: phosphoribosylglycinamide formyltransferase 2
Primary source: ECOCYC:EG11809
Locus tag: b1849
See related: ASAP:ABE-0006162
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK1850
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NC_000913.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Studies revealed that a simultaneous presence of both the genes fhs and purT confers growth disadvantage compared to when present in single
Title: Simultaneous presence of fhs and purT genes is disadvantageous for the fitness of Escherichia coli growth.
N-terminus verified by Edman degradation on mature peptide
Title: Cloning and characterization of a new purine biosynthetic enzyme: a non-folate glycinamide ribonucleotide transformylase from E. coli.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables acetate kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables acetate kinase activity	IEA Inferred from Electronic Annotation more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables ligase activity	IEA Inferred from Electronic Annotation more info
enables magnesium ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables phosphoribosylglycinamide formyltransferase 2 activity	IEA Inferred from Electronic Annotation more info
enables phosphoribosylglycinamide formyltransferase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in 'de novo' IMP biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in purine nucleotide biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in purine ribonucleotide biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed

NP_416363.1

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The following sections contain reference sequences that belong to a specific genome build. Explain