Tekt2 tektin 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tekt2provided by RGD
Official Full Name: tektin 2provided by RGD
Primary source: RGD:1311065
See related: EnsemblRapid:ENSRNOG00000011033 AllianceGenome:RGD:1311065
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in cilium assembly and flagellated sperm motility. Predicted to act upstream of or within inner dynein arm assembly. Predicted to be located in axonemal microtubule and microtubule organizing center. Predicted to be active in axonemal A tubule inner sheath and sperm flagellum. Orthologous to human TEKT2 (tektin 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 394.6) See more
Orthologs: human mouse all
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Genomic context

Location:: 5q36

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (143904185..143907724, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (138619665..138623301, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (144341955..144345500, complement)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

TEKT2 may function as an ODF-affiliated molecule required for flagellum stability and sperm motility.
Title: Subcellular localization of Tektin2 in rat sperm flagellum.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Tekt2 (e-PCR), detects polymorphism
- UniSTS:525517

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in cilium assembly	IEA Inferred from Electronic Annotation more info
involved_in cilium movement involved in cell motility	IBA Inferred from Biological aspect of Ancestor more info
involved_in flagellated sperm motility	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within flagellated sperm motility	ISO Inferred from Sequence Orthology more info
involved_in flagellated sperm motility	ISO Inferred from Sequence Orthology more info
involved_in flagellated sperm motility	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within inner dynein arm assembly	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in axonemal A tubule inner sheath	ISO Inferred from Sequence Orthology more info
is_active_in axonemal A tubule inner sheath	ISS Inferred from Sequence or Structural Similarity more info
located_in axonemal microtubule	ISO Inferred from Sequence Orthology more info
located_in axonemal microtubule	ISS Inferred from Sequence or Structural Similarity more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in microtubule	IEA Inferred from Electronic Annotation more info
is_active_in microtubule cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
located_in microtubule organizing center	ISO Inferred from Sequence Orthology more info
located_in microtubule organizing center	ISS Inferred from Sequence or Structural Similarity more info
located_in sperm flagellum	IEA Inferred from Electronic Annotation more info
is_active_in sperm flagellum	ISO Inferred from Sequence Orthology more info
is_active_in sperm flagellum	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: tektin-2

Names: tektin 2 (testicular); tektin-t; testicular tektin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.