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    Smim5 small integral membrane protein 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 689926, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Smim5provided by RGD
    Official Full Name
    small integral membrane protein 5provided by RGD
    Primary source
    RGD:1586374
    See related
    EnsemblRapid:ENSRNOG00000049642 AllianceGenome:RGD:1586374
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in membrane. Orthologous to human SMIM5 (small integral membrane protein 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 54.3), Spleen (RPKM 27.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Smim5 in Genome Data Viewer
    Location:
    10q32.1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (101632966..101642089)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (101134033..101139814)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (104451222..104457002)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene LLGL scribble cell polarity complex component 2 Neighboring gene myosin XVB Neighboring gene RecQ like helicase 5 Neighboring gene endoregulin Neighboring gene SAP30 binding protein Neighboring gene ribosomal protein S18-like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    small integral membrane protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163002.2 → NP_001156474.1  small integral membrane protein 5

      See identical proteins and their annotated locations for NP_001156474.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A6HKS2, M0R3V6
      Conserved Domains (1) summary
      pfam15831
      Location:25 → 51
      DUF4713; Domain of unknown function (DUF4713)

    2. NM_001277479.2 → NP_001264408.1  small integral membrane protein 5

      See identical proteins and their annotated locations for NP_001264408.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A6HKS2, M0R3V6
      Related
      ENSRNOP00000070334.1, ENSRNOT00000088665.3
      Conserved Domains (1) summary
      pfam15831
      Location:25 → 51
      DUF4713; Domain of unknown function (DUF4713)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      101632966..101642089
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_010055259.1 RNA Sequence

    2. XR_010055260.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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