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    Szrd1 SUZ RNA binding domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500575, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Szrd1provided by RGD
    Official Full Name
    SUZ RNA binding domain containing 1provided by RGD
    Primary source
    RGD:1560286
    See related
    EnsemblRapid:ENSRNOG00000009183 AllianceGenome:RGD:1560286
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    C1orf144; RGD1560286
    Summary
    Orthologous to human SZRD1 (SUZ RNA binding domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Muscle (RPKM 251.9), Kidney (RPKM 220.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Szrd1 in Genome Data Viewer
    Location:
    5q36
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (158701753..158726276, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (153418748..153443286, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (159638259..159662790, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene spermatogenesis associated 21 Neighboring gene uncharacterized LOC134487027 Neighboring gene uncharacterized LOC134487028 Neighboring gene F-box protein 42

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    SUZ RNA-binding domain-containing; SUZ domain-containing protein 1
    Names
    UPF0485 protein C1orf144 homolog
    putative MAPK activating protein PM20,PM21

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001114599.2 → NP_001108071.1  SUZ RNA-binding domain-containing

      See identical proteins and their annotated locations for NP_001108071.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the protein.
      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/Swiss-Prot
      Q5XIA2
      UniProtKB/TrEMBL
      A6ITR5
      Related
      ENSRNOP00000048348.3, ENSRNOT00000045226.7
      Conserved Domains (2) summary
      pfam12752
      Location:56 → 107
      SUZ; SUZ domain
      pfam12901
      Location:119 → 151
      SUZ-C; SUZ-C motif

    RNA

    1. NR_102345.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      JAXUCZ010000005

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      158701753..158726276 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006239264.5 → XP_006239326.1  SUZ domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006239326.1

      Conserved Domains (2) summary
      pfam12752
      Location:55 → 106
      SUZ; SUZ domain
      pfam12901
      Location:118 → 150
      SUZ-C; SUZ-C motif

    RNA

    1. XR_354340.5 RNA Sequence

    2. XR_354339.5 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XIA2.2 GenPept UniProtKB/Swiss-Prot:Q5XIA2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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