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    moaB protein MoaB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945396, updated on 3-Dec-2024

    Summary

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    Official Symbol
    moaB
    Official Full Name
    protein MoaB
    Primary source
    ECOCYC:EG11596
    Locus tag
    b0782
    See related
    ASAP:ABE-0002671
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    chlA2; ECK0771
    Summary
    HT_Cmplx43_Mem: [More information is available at EcoGene: EG11596]. Molybdenum and tungsten cofactors of all enzymes that require one or the other for activity are present in an oxidized state as molybdate or tungstate ions that are chelated by the cis-dithiolene moiety of a molybdenum cofactor. [More information is available at EcoCyc: EG11596].
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    Genomic context

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    Sequence:
    NC_000913.3 (818055..818567)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transferase YbhK Neighboring gene GTP 3',8'-cyclase Neighboring gene cyclic pyranopterin monophosphate synthase Neighboring gene molybdopterin synthase sulfur carrier subunit Neighboring gene molybdopterin synthase catalytic subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic characterization of moaB mutants of Escherichia coli. Kozmin SG, et al. Res Microbiol, 2013 Sep. PMID 23680484, Free PMC Article
    2. Rearrangement reactions in the biosynthesis of molybdopterin--an NMR study with multiply 13C/15N labelled precursors. Rieder C, et al. Eur J Biochem, 1998 Jul 1. PMID 9692897
    3. Molecular genetic analysis of the moa operon of Escherichia coli K-12 required for molybdenum cofactor biosynthesis. Rivers SL, et al. Mol Microbiol, 1993 Jun. PMID 8361352
    4. Characterization of the ModE DNA-binding sites in the control regions of modABCD and moaABCDE of Escherichia coli. McNicholas PM, et al. Mol Microbiol, 1997 Feb. PMID 9044285
    5. Proposed nomenclature for the genes involved in molybdenum metabolism in Escherichia coli and Salmonella typhimurium. Shanmugam KT, et al. Mol Microbiol, 1992 Nov. PMID 1484496

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Transposon insertions in moaB caused partial molybdenum cofactor deficiency associated with chlorate-resistance but not for 6-N-hydroxylaminopurine sensitivity.
      Title: Genetic characterization of moaB mutants of Escherichia coli.
    2. N-terminus verified by Edman degradation on mature peptide
      Title: Molecular genetic analysis of the moa operon of Escherichia coli K-12 required for molybdenum cofactor biosynthesis.
    3. X-ray crystallography of MoaB protein from Escherichia coli
      Title: Structure of the molybdenum-cofactor biosynthesis protein MoaB of Escherichia coli.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Mo-molybdopterin cofactor biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein hexamerization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein MoaB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      818055..818567
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415303.1 protein MoaB [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415303.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A418GNS9
      Conserved Domains (1) summary
      TIGR02667
      Location:7 → 169
      moaB_proteo; molybdenum cofactor biosynthesis protein B, proteobacterial
    Nucleotide Protein
    Heading Accession and Version

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