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    tehB tellurite methyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945979, updated on 17-Dec-2024

    Summary

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    Official Symbol
    tehB
    Official Full Name
    tellurite methyltransferase
    Primary source
    ECOCYC:EG11884
    Locus tag
    b1430
    See related
    ASAP:ABE-0004772
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1423
    Summary
    The TehB protein in conjunction with TehA confers resistance to tellurite when expressed on a multicopy plasmid . [More information is available at EcoCyc: EG11884].
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    Genomic context

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    Sequence:
    NC_000913.3 (1501562..1502155)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF465 domain-containing protein YdcH Neighboring gene ribosomal-protein-L12-serine N-acetyltransferase Neighboring gene putative acyltransferase YdcK Neighboring gene tellurite resistance protein Neighboring gene DUF3313 domain-containing lipoprotein YdcL Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure and mechanism of the chalcogen-detoxifying protein TehB from Escherichia coli. Choudhury HG, et al. Biochem J, 2011 Apr 1. PMID 21244361
    2. The tellurite-resistance determinants tehAtehB and klaAklaBtelB have different biochemical requirements. Turner RJ, et al. Microbiology (Reading), 1995 Dec. PMID 8574407
    3. Escherichia coli TehB requires S-adenosylmethionine as a cofactor to mediate tellurite resistance. Liu M, et al. J Bacteriol, 2000 Nov. PMID 11053398, Free PMC Article
    4. The role of cysteine residues in tellurite resistance mediated by the TehAB determinant. Dyllick-Brenzinger M, et al. Biochem Biophys Res Commun, 2000 Oct 22. PMID 11032735
    5. Expression of Escherichia coli TehA gives resistance to antiseptics and disinfectants similar to that conferred by multidrug resistance efflux pumps. Turner RJ, et al. Antimicrob Agents Chemother, 1997 Feb. PMID 9021204, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables S-adenosylmethionine-dependent methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables S-adenosylmethionine-dependent methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to antibiotic IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to tellurium ion IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to tellurium ion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to toxic substance IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tellurite methyltransferase
    NP_415947.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1501562..1502155
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415947.1 tellurite methyltransferase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415947.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376M7W5, A0A5B9AK88, A0A7A3FC88
      Conserved Domains (1) summary
      PRK11207
      Location:1 → 196
      PRK11207; tellurite resistance methyltransferase TehB
    Nucleotide Protein
    Heading Accession and Version

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