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    ytfK stringent response modulator YtfK [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948736, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ytfK
    Official Full Name
    stringent response modulator YtfK
    Primary source
    ECOCYC:G7872
    Locus tag
    b4217
    See related
    ASAP:ABE-0013797
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4213
    Summary
    PhoB regulon (Baek, 2006). [More information is available at EcoGene: EG12511]. Expression of ytfK is activated by PhoB . [More information is available at EcoCyc: G7872].
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    Genomic context

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    Sequence:
    NC_000913.3 (4439587..4439793)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein YtfI Neighboring gene PF09695 family protein YtfJ Neighboring gene putative cadaverine/putrescine exporter Neighboring gene methionine sulfoxide reductase A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Involvement of the ytfK gene from the PhoB regulon in stationary-phase H2O2 stress tolerance in Escherichia coli. Iwadate Y, et al. Microbiology (Reading), 2017 Dec. PMID 29148366
    2. YtfK activates the stringent response by triggering the alarmone synthetase SpoT in Escherichia coli. Germain E, et al. Nat Commun, 2019 Dec 17. PMID 31848343, Free PMC Article
    3. Novel gene members in the Pho regulon of Escherichia coli. Baek JH, et al. FEMS Microbiol Lett, 2006 Nov. PMID 17020555
    4. SigmaS-dependent gene expression at the onset of stationary phase in Escherichia coli: function of sigmaS-dependent genes and identification of their promoter sequences. Lacour S, et al. J Bacteriol, 2004 Nov. PMID 15489429, Free PMC Article
    5. Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes. Burland V, et al. Nucleic Acids Res, 1995 Jun 25. PMID 7610040, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to phosphate starvation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within stringent response IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    stringent response modulator YtfK

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4439587..4439793
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418638.2 stringent response modulator YtfK [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418638.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0H3JIS0, A0AAJ3NXC6, C3SFI2
      Conserved Domains (1) summary
      pfam06526
      Location:1 → 63
      DUF1107; Protein of unknown function (DUF1107)
    Nucleotide Protein
    Heading Accession and Version

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