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    Ptprd protein tyrosine phosphatase receptor type D [ Mus musculus (house mouse) ]

    Gene ID: 19266, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ptprdprovided by MGI
    Official Full Name
    protein tyrosine phosphatase receptor type Dprovided by MGI
    Primary source
    MGI:MGI:97812
    See related
    Ensembl:ENSMUSG00000028399 AllianceGenome:MGI:97812
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    R-PTP-delta; 1110002J03Rik; 3000002J10Rik; B230219D21Rik
    Summary
    Enables cell adhesion molecule binding activity and signaling receptor binding activity. Involved in several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; regulation of synapse organization; and synapse organization. Acts upstream of or within negative regulation of receptor signaling pathway via JAK-STAT and regulation of immune response. Is active in several cellular components, including Schaffer collateral - CA1 synapse; hippocampal mossy fiber to CA3 synapse; and presynaptic membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in coronary artery disease; diabetes mellitus; hypertension; and type 2 diabetes mellitus. Orthologous to human PTPRD (protein tyrosine phosphatase receptor type D). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in CNS E18 (RPKM 18.0), cortex adult (RPKM 16.4) and 18 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ptprd in Genome Data Viewer
    Location:
    4 C3; 4 36.94 cM
    Exon count:
    50
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (75859474..78132282, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (75941237..78211742, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_10563 Neighboring gene ribosomal protein L7A pseudogene Neighboring gene malate dehydrogenase 2, NAD (mitochondrial) pseudogene Neighboring gene STARR-seq mESC enhancer starr_10567 Neighboring gene STARR-seq mESC enhancer starr_10568 Neighboring gene predicted gene, 46893 Neighboring gene STARR-seq mESC enhancer starr_10569 Neighboring gene predicted gene, 42303 Neighboring gene STARR-seq mESC enhancer starr_10570 Neighboring gene STARR-seq mESC enhancer starr_10571 Neighboring gene component of oligomeric golgi complex 5 pseudogene Neighboring gene predicted gene, 42302 Neighboring gene ribosomal protein L27A pseudogene Neighboring gene developmentally regulated GTP binding protein 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_10572 Neighboring gene STARR-seq mESC enhancer starr_10573 Neighboring gene predicted gene, 38646 Neighboring gene FK506 binding protein 1a, pseudogene 4 Neighboring gene RIKEN cDNA B230208B08 gene Neighboring gene zinc finger, CCHC domain containing 9 pseudogene Neighboring gene predicted gene, 32545

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Loss of protein tyrosine phosphatase receptor delta PTPRD increases the number of cortical neurons, impairs synaptic function and induces autistic-like behaviors in adult mice. Cortés BI, et al. Biol Res, 2024 Jun 18. PMID 38890753, Free PMC Article
    2. Developmental regulation of gene expression for the MPTP delta isoforms in the central nervous system and the immune system. Mizuno K, et al. FEBS Lett, 1994 Dec 5. PMID 7988677
    3. Receptor protein tyrosine phosphatase delta is not essential for synapse maintenance or transmission at hippocampal synapses. Han KA, et al. Mol Brain, 2020 Jun 17. PMID 32552840, Free PMC Article
    4. Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist. Uhl GR, et al. Proc Natl Acad Sci U S A, 2018 Nov 6. PMID 30348770, Free PMC Article
    5. PTPδ is a presynaptic organizer for the formation and maintenance of climbing fiber to Purkinje cell synapses in the developing cerebellum. Okuno Y, et al. Front Mol Neurosci, 2023. PMID 37426069, Free PMC Article

    See all (88) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Loss of protein tyrosine phosphatase receptor delta PTPRD increases the number of cortical neurons, impairs synaptic function and induces autistic-like behaviors in adult mice.
      Title: Loss of protein tyrosine phosphatase receptor delta PTPRD increases the number of cortical neurons, impairs synaptic function and induces autistic-like behaviors in adult mice.
    2. Mice lacking Ptprd exhibit deficits in goal-directed behavior and female-specific impairments in sensorimotor gating.
      Title: Mice lacking Ptprd exhibit deficits in goal-directed behavior and female-specific impairments in sensorimotor gating.
    3. Protein tyrosine phosphatase receptor delta serves as the orexigenic asprosin receptor.
      Title: Protein tyrosine phosphatase receptor δ serves as the orexigenic asprosin receptor.
    4. Intact synapse structure and function after combined knockout of PTPdelta, PTPsigma, and LAR.
      Title: Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.
    5. Structure-activity studies of PTPRD phosphatase inhibitors identify a 7-cyclopentymethoxy illudalic acid analog candidate for development.
      Title: Structure-activity studies of PTPRD phosphatase inhibitors identify a 7-cyclopentymethoxy illudalic acid analog candidate for development.
    6. Receptor protein tyrosine phosphatase delta is not essential for synapse maintenance or transmission at hippocampal synapses.
      Title: Receptor protein tyrosine phosphatase delta is not essential for synapse maintenance or transmission at hippocampal synapses.
    7. The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis.
      Title: The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis.
    8. Roles of Collagen XXV and Its Putative Receptors PTPsigma/delta in Intramuscular Motor Innervation and Congenital Cranial Dysinnervation Disorder.
      Title: Roles of Collagen XXV and Its Putative Receptors PTPσ/δ in Intramuscular Motor Innervation and Congenital Cranial Dysinnervation Disorder.
    9. Cocaine reward is reduced by decreased expression of PTPRD and by a novel PTPRD antagonist.
      Title: Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist.
    10. We show that PTP-3, a LAR homolog in Caenorhabditis elegans, participates in Sema2A-regulated axon guidance. PTPdelta, a member of vertebrate LAR class PTPs, is involved in Sema3A-regulated cortical dendritic growth. In Sema3A signaling, PTPdelta activates Fyn and Src kinases by dephosphorylating their C-terminal Tyr residues.
      Title: Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase.
    Submit: New GeneRIF Correction See all GeneRIFs (16)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC36851, MGC113757

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cell adhesion molecule binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables histone H2AXY142 phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables non-membrane spanning protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein tyrosine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein tyrosine phosphatase activity, metal-dependent IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables signaling receptor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to hypoxia IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cellular response to platelet-derived growth factor stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in modulation of chemical synaptic transmission IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in modulation of chemical synaptic transmission IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of receptor signaling pathway via JAK-STAT IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nervous system development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in neuron differentiation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of dendrite morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of dendritic spine morphogenesis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of synapse assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in presynapse assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in presynaptic membrane assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in presynaptic membrane assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of immune response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of postsynaptic density assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of postsynaptic density assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of postsynaptic density assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synaptic membrane adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synaptic membrane adhesion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in synaptic membrane adhesion ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in trans-synaptic signaling IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in trans-synaptic signaling IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in trans-synaptic signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in trans-synaptic signaling by trans-synaptic complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in trans-synaptic signaling by trans-synaptic complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Schaffer collateral - CA1 synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in Schaffer collateral - CA1 synapse IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    is_active_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in hippocampal mossy fiber to CA3 synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in hippocampal mossy fiber to CA3 synapse IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    is_active_in presynaptic membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in presynaptic membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    receptor-type tyrosine-protein phosphatase delta
    NP_001339557.1
    NP_001339558.1
    NP_001339559.1
    NP_001355920.1
    NP_001355921.1
    NP_001355922.1
    NP_035341.2
    XP_011248265.1
    XP_030109195.1
    XP_030109196.1
    XP_030109197.1
    XP_030109199.1
    XP_030109201.1
    XP_036019731.1
    XP_036019732.1
    XP_036019733.1
    XP_036019734.1
    XP_036019735.1
    XP_036019736.1
    XP_036019737.1
    XP_036019738.1
    XP_036019739.1
    XP_036019740.1
    XP_036019741.1
    XP_036019742.1
    XP_036019743.1
    XP_036019744.1
    XP_036019745.1
    XP_036019746.1
    XP_036019747.1
    XP_036019749.1
    XP_036019750.1
    XP_036019751.1
    XP_036019752.1
    XP_036019753.1
    XP_036019754.1
    XP_036019755.1
    XP_036019756.1
    XP_036019757.1
    XP_036019758.1
    XP_036019759.1
    XP_036019760.1
    XP_036019761.1
    XP_036019762.1
    XP_036019763.1
    XP_036019764.1
    XP_036019766.1
    XP_036019767.1
    XP_036019768.1
    XP_036019769.1
    XP_036019770.1
    XP_036019771.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001352628.1 → NP_001339557.1  receptor-type tyrosine-protein phosphatase delta isoform 2 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and has multiple differences in the coding region, but maintains the reading frame, compared to variant 1. This variant encodes isoform 2, which has the same N- and C-termini, but is longer than isoform 1.
      Source sequence(s)
      AF326559, AL845517, AL929181, BC086654, CJ057541
      UniProtKB/TrEMBL
      E9Q7I7
      Conserved Domains (6) summary
      cd05739
      Location:251 → 319
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd00063
      Location:324 → 413
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05738
      Location:150 → 227
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd14624
      Location:938 → 1221
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1222 → 1513
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain

    2. NM_001352629.1 → NP_001339558.1  receptor-type tyrosine-protein phosphatase delta isoform 3 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and has multiple differences in the coding region, but maintains the reading frame, compared to variant 1. This variant encodes isoform 3, which has the same N- and C-termini, but is shorter than isoform 1.
      Source sequence(s)
      AF326559, AL845517, AL929181, BC086654, CJ057541
      UniProtKB/TrEMBL
      G3UYU6
      Conserved Domains (6) summary
      cd05739
      Location:251 → 319
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd00063
      Location:324 → 413
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05738
      Location:150 → 227
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd14624
      Location:925 → 1208
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1209 → 1500
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain

    3. NM_001352630.1 → NP_001339559.1  receptor-type tyrosine-protein phosphatase delta isoform 4 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR and has multiple differences in the coding region, but maintains the reading frame, compared to variant 1. This variant encodes isoform 4, which has the same N- and C-termini, but is shorter than isoform 1.
      Source sequence(s)
      AF326559, AL929181, BC086654, CJ057541
      UniProtKB/TrEMBL
      G3UYU6
      Related
      ENSMUSP00000134229.2, ENSMUST00000174531.8
      Conserved Domains (6) summary
      cd05739
      Location:251 → 319
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd00063
      Location:324 → 413
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05738
      Location:150 → 227
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd14624
      Location:924 → 1207
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1208 → 1499
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain

    4. NM_001368991.1 → NP_001355920.1  receptor-type tyrosine-protein phosphatase delta isoform 5 precursor

      Status: VALIDATED

      Source sequence(s)
      AL844848, AL845158, AL845333, AL845496, AL845508, AL845517, AL928645, AL929181, AL954189, AL954376, AL954675
      UniProtKB/TrEMBL
      G3UWK6
      Conserved Domains (6) summary
      cd05739
      Location:257 → 325
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd00063
      Location:330 → 419
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05738
      Location:150 → 233
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      cd14624
      Location:929 → 1212
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1213 → 1504
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2

    5. NM_001368992.1 → NP_001355921.1  receptor-type tyrosine-protein phosphatase delta isoform 6 precursor

      Status: VALIDATED

      Source sequence(s)
      AL844848, AL845517, AL929181
      UniProtKB/TrEMBL
      G3UYU6
      Conserved Domains (6) summary
      cd05739
      Location:247 → 315
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd00063
      Location:320 → 409
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05738
      Location:150 → 227
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd14624
      Location:921 → 1204
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1205 → 1496
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain

    6. NM_001368993.1 → NP_001355922.1  receptor-type tyrosine-protein phosphatase delta isoform 7 precursor

      Status: VALIDATED

      Source sequence(s)
      AL844848, AL845517, AL929181
      UniProtKB/TrEMBL
      E9Q7I7
      Related
      ENSMUSP00000058466.10, ENSMUST00000050757.16
      Conserved Domains (6) summary
      cd05739
      Location:247 → 315
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd00063
      Location:320 → 409
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05738
      Location:150 → 227
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd14624
      Location:934 → 1217
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1218 → 1509
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain

    7. NM_001428308.1 → NP_001415237.1  receptor-type tyrosine-protein phosphatase delta isoform 8 precursor

      Status: VALIDATED

      Source sequence(s)
      AL844848, AL845158, AL845333, AL845496, AL845508, AL845517, AL928645, AL929181, AL954189, AL954376, AL954675
      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0

    8. NM_011211.4 → NP_035341.2  receptor-type tyrosine-protein phosphatase delta isoform 1 precursor

      See identical proteins and their annotated locations for NP_035341.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes isoform 1.
      Source sequence(s)
      AL844848, AL845158, AL845333, AL845496, AL845508, AL845517, AL928645, AL929181, AL954189, AL954376, AL954675
      Consensus CDS
      CCDS57280.1
      UniProtKB/TrEMBL
      B9EJA3, G3UWK6
      Related
      ENSMUSP00000133468.3, ENSMUST00000173376.9
      Conserved Domains (8) summary
      cd05738
      Location:150 → 233
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd05739
      Location:257 → 325
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:952 → 1207
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00410
      Location:139 → 232
      IG_like; Immunoglobulin like
      cd00047
      Location:978 → 1207
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:330 → 419
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:48 → 122
      Ig; Immunoglobulin domain

    RNA

    1. NR_160919.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL844848, AL845158, AL845333, AL845496, AL845508, AL845517, AL928645, AL929181, AL954189, AL954376, AL954675

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      75859474..78132282 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163859.1 → XP_036019752.1  receptor-type tyrosine-protein phosphatase delta isoform X24

      UniProtKB/TrEMBL
      G3UY75
      Conserved Domains (7) summary
      cd00063
      Location:916 → 1007
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1343 → 1626
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1627 → 1918
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:134 → 224
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:233 → 314
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    2. XM_036163844.1 → XP_036019737.1  receptor-type tyrosine-protein phosphatase delta isoform X7

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (7) summary
      cd00063
      Location:926 → 1017
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1384 → 1667
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1668 → 1959
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:134 → 230
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:243 → 324
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    3. XM_036163845.1 → XP_036019738.1  receptor-type tyrosine-protein phosphatase delta isoform X8

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (7) summary
      cd00063
      Location:923 → 1014
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1381 → 1664
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1665 → 1956
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:134 → 227
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:240 → 321
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    4. XM_036163861.1 → XP_036019754.1  receptor-type tyrosine-protein phosphatase delta isoform X27

      Related
      ENSMUSP00000102910.3, ENSMUST00000107289.9
      Conserved Domains (7) summary
      cd00063
      Location:929 → 1020
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1341 → 1624
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1625 → 1916
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:134 → 233
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:246 → 327
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    5. XM_036163854.1 → XP_036019747.1  receptor-type tyrosine-protein phosphatase delta isoform X19

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (8) summary
      cd00063
      Location:929 → 1020
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1346 → 1629
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1630 → 1921
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam00041
      Location:619 → 706
      fn3; Fibronectin type III domain
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:134 → 233
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:246 → 327
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    6. XM_036163847.1 → XP_036019740.1  receptor-type tyrosine-protein phosphatase delta isoform X10

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (7) summary
      cd00063
      Location:929 → 1020
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1361 → 1644
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1645 → 1936
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:134 → 233
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:246 → 327
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    7. XM_036163840.1 → XP_036019733.1  receptor-type tyrosine-protein phosphatase delta isoform X3

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (7) summary
      cd00063
      Location:929 → 1020
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1387 → 1670
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1671 → 1962
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:134 → 233
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:246 → 327
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    8. XM_036163858.1 → XP_036019751.1  receptor-type tyrosine-protein phosphatase delta isoform X23

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (8) summary
      cd00063
      Location:926 → 1017
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1343 → 1626
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1627 → 1918
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam00041
      Location:616 → 703
      fn3; Fibronectin type III domain
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:243 → 324
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    9. XM_036163856.1 → XP_036019749.1  receptor-type tyrosine-protein phosphatase delta isoform X21

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (8) summary
      cd00063
      Location:921 → 1012
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1346 → 1629
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1630 → 1921
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      pfam18861
      Location:1199 → 1291
      PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    10. XM_030253341.2 → XP_030109201.1  receptor-type tyrosine-protein phosphatase delta isoform X35

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (6) summary
      cd05739
      Location:258 → 326
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd00063
      Location:921 → 1012
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05738
      Location:151 → 234
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd14624
      Location:1336 → 1619
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1620 → 1911
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain

    11. XM_036163868.1 → XP_036019761.1  receptor-type tyrosine-protein phosphatase delta isoform X34

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (8) summary
      cd00063
      Location:921 → 1012
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1337 → 1620
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1621 → 1912
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      pfam18861
      Location:1199 → 1289
      PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    12. XM_030253336.2 → XP_030109196.1  receptor-type tyrosine-protein phosphatase delta isoform X17

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (6) summary
      cd05739
      Location:258 → 326
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd00063
      Location:921 → 1012
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05738
      Location:151 → 234
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd14624
      Location:1347 → 1630
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1631 → 1922
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain

    13. XM_036163866.1 → XP_036019759.1  receptor-type tyrosine-protein phosphatase delta isoform X32

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (7) summary
      cd00063
      Location:921 → 1012
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1337 → 1620
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1621 → 1912
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    14. XM_036163865.1 → XP_036019758.1  receptor-type tyrosine-protein phosphatase delta isoform X31

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (7) summary
      cd00063
      Location:921 → 1012
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1338 → 1621
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1622 → 1913
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    15. XM_036163867.1 → XP_036019760.1  receptor-type tyrosine-protein phosphatase delta isoform X33

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (8) summary
      cd00063
      Location:921 → 1012
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1337 → 1620
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1621 → 1912
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      pfam18861
      Location:1200 → 1292
      PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    16. XM_036163851.1 → XP_036019744.1  receptor-type tyrosine-protein phosphatase delta isoform X14

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (7) summary
      cd00063
      Location:921 → 1012
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1348 → 1631
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1632 → 1923
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    17. XM_036163864.1 → XP_036019757.1  receptor-type tyrosine-protein phosphatase delta isoform X30

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (7) summary
      cd00063
      Location:921 → 1012
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1338 → 1621
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1622 → 1913
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    18. XM_036163863.1 → XP_036019756.1  receptor-type tyrosine-protein phosphatase delta isoform X29

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (7) summary
      cd00063
      Location:921 → 1012
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1339 → 1622
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1623 → 1914
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    19. XM_036163862.1 → XP_036019755.1  receptor-type tyrosine-protein phosphatase delta isoform X28

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (9) summary
      cd00063
      Location:930 → 1021
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1341 → 1624
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1625 → 1916
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam00041
      Location:620 → 707
      fn3; Fibronectin type III domain
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      pfam18861
      Location:1208 → 1300
      PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    20. XM_030253339.2 → XP_030109199.1  receptor-type tyrosine-protein phosphatase delta isoform X25

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (6) summary
      cd05739
      Location:258 → 326
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd00063
      Location:930 → 1021
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05738
      Location:151 → 234
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd14624
      Location:1342 → 1625
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1626 → 1917
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain

    21. XM_036163849.1 → XP_036019742.1  receptor-type tyrosine-protein phosphatase delta isoform X12

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (7) summary
      cd00063
      Location:930 → 1021
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1356 → 1639
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1640 → 1931
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    22. XM_036163853.1 → XP_036019746.1  receptor-type tyrosine-protein phosphatase delta isoform X18

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (8) summary
      cd00063
      Location:930 → 1021
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1346 → 1629
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1630 → 1921
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam00041
      Location:620 → 707
      fn3; Fibronectin type III domain
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    23. XM_036163852.1 → XP_036019745.1  receptor-type tyrosine-protein phosphatase delta isoform X16

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (7) summary
      cd00063
      Location:930 → 1021
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1347 → 1630
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1631 → 1922
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    24. XM_036163841.1 → XP_036019734.1  receptor-type tyrosine-protein phosphatase delta isoform X4

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (7) summary
      cd00063
      Location:930 → 1021
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1387 → 1670
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1671 → 1962
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    25. XM_036163860.1 → XP_036019753.1  receptor-type tyrosine-protein phosphatase delta isoform X26

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (9) summary
      cd00063
      Location:930 → 1021
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1342 → 1625
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1626 → 1917
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam00041
      Location:620 → 707
      fn3; Fibronectin type III domain
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      pfam18861
      Location:1209 → 1301
      PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    26. XM_030253337.2 → XP_030109197.1  receptor-type tyrosine-protein phosphatase delta isoform X20

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (6) summary
      cd05739
      Location:258 → 326
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd00063
      Location:930 → 1021
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05738
      Location:151 → 234
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd14624
      Location:1346 → 1629
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1630 → 1921
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain

    27. XM_036163843.1 → XP_036019736.1  receptor-type tyrosine-protein phosphatase delta isoform X6

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (8) summary
      cd00063
      Location:930 → 1021
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1386 → 1669
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1670 → 1961
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      pfam18861
      Location:1209 → 1301
      PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    28. XM_036163842.1 → XP_036019735.1  receptor-type tyrosine-protein phosphatase delta isoform X5

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (8) summary
      cd00063
      Location:930 → 1021
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1387 → 1670
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1671 → 1962
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      pfam18861
      Location:1209 → 1299
      PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    29. XM_036163857.1 → XP_036019750.1  receptor-type tyrosine-protein phosphatase delta isoform X22

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (8) summary
      cd00063
      Location:930 → 1021
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1343 → 1626
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1627 → 1918
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam00041
      Location:620 → 707
      fn3; Fibronectin type III domain
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    30. XM_036163848.1 → XP_036019741.1  receptor-type tyrosine-protein phosphatase delta isoform X11

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (7) summary
      cd00063
      Location:930 → 1021
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1357 → 1640
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1641 → 1932
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    31. XM_030253335.2 → XP_030109195.1  receptor-type tyrosine-protein phosphatase delta isoform X15

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (6) summary
      cd05739
      Location:258 → 326
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd00063
      Location:930 → 1021
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05738
      Location:151 → 234
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd14624
      Location:1347 → 1630
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1631 → 1922
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain

    32. XM_036163839.1 → XP_036019732.1  receptor-type tyrosine-protein phosphatase delta isoform X2

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (7) summary
      cd00063
      Location:930 → 1021
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1387 → 1670
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1671 → 1962
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    33. XM_036163850.1 → XP_036019743.1  receptor-type tyrosine-protein phosphatase delta isoform X13

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (8) summary
      cd00063
      Location:930 → 1021
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1348 → 1631
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1632 → 1923
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam00041
      Location:620 → 707
      fn3; Fibronectin type III domain
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    34. XM_036163846.1 → XP_036019739.1  receptor-type tyrosine-protein phosphatase delta isoform X9

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (7) summary
      cd00063
      Location:930 → 1021
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1362 → 1645
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1646 → 1937
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    35. XM_036163838.1 → XP_036019731.1  receptor-type tyrosine-protein phosphatase delta isoform X1

      UniProtKB/Swiss-Prot
      G3X9S7, Q64486, Q64487, Q64488, Q64495, Q8VBV0
      Conserved Domains (7) summary
      cd00063
      Location:930 → 1021
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1388 → 1671
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1672 → 1963
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 123
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:135 → 234
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:247 → 328
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    36. XM_036163877.1 → XP_036019770.1  receptor-type tyrosine-protein phosphatase delta isoform X43

      UniProtKB/TrEMBL
      G3UYU6
      Conserved Domains (7) summary
      cd00063
      Location:317 → 406
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:918 → 1201
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1202 → 1493
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:134 → 224
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:233 → 314
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    37. XM_036163874.1 → XP_036019767.1  receptor-type tyrosine-protein phosphatase delta isoform X41

      UniProtKB/TrEMBL
      G3UY75
      Conserved Domains (8) summary
      cd00063
      Location:907 → 998
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1318 → 1601
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1602 → 1893
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      pfam18861
      Location:1185 → 1277
      PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:134 → 224
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:233 → 314
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    38. XM_011249963.2 → XP_011248265.1  receptor-type tyrosine-protein phosphatase delta isoform X39

      UniProtKB/TrEMBL
      G3UY75
      Related
      ENSMUSP00000133973.2, ENSMUST00000174180.8
      Conserved Domains (6) summary
      cd05739
      Location:244 → 312
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd00063
      Location:907 → 998
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05738
      Location:150 → 224
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd14624
      Location:1319 → 1602
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1603 → 1894
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain

    39. XM_036163873.1 → XP_036019766.1  receptor-type tyrosine-protein phosphatase delta isoform X40

      UniProtKB/TrEMBL
      G3UY75
      Conserved Domains (8) summary
      cd00063
      Location:907 → 998
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1319 → 1602
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1603 → 1894
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      pfam18861
      Location:1186 → 1278
      PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:134 → 224
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:233 → 314
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    40. XM_036163871.1 → XP_036019764.1  receptor-type tyrosine-protein phosphatase delta isoform X38

      UniProtKB/TrEMBL
      G3UY75
      Conserved Domains (7) summary
      cd00063
      Location:907 → 998
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1320 → 1603
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1604 → 1895
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:134 → 224
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:233 → 314
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    41. XM_036163869.1 → XP_036019762.1  receptor-type tyrosine-protein phosphatase delta isoform X36

      UniProtKB/TrEMBL
      G3UY75
      Conserved Domains (7) summary
      cd00063
      Location:907 → 998
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1334 → 1617
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1618 → 1909
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:134 → 224
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:233 → 314
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    42. XM_036163870.1 → XP_036019763.1  receptor-type tyrosine-protein phosphatase delta isoform X37

      UniProtKB/TrEMBL
      G3UY75
      Conserved Domains (8) summary
      cd00063
      Location:916 → 1007
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:1328 → 1611
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1612 → 1903
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam00041
      Location:606 → 693
      fn3; Fibronectin type III domain
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:134 → 224
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:233 → 314
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    43. XM_036163875.1 → XP_036019768.1  receptor-type tyrosine-protein phosphatase delta isoform X42

      UniProtKB/TrEMBL
      E9Q7I7
      Conserved Domains (7) summary
      cd00063
      Location:317 → 406
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:931 → 1214
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1215 → 1506
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:134 → 224
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:233 → 314
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    44. XM_036163878.1 → XP_036019771.1  receptor-type tyrosine-protein phosphatase delta isoform X44

      UniProtKB/TrEMBL
      G3UYU6
      Related
      ENSMUSP00000099898.2, ENSMUST00000102834.8
      Conserved Domains (7) summary
      cd00063
      Location:317 → 406
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:917 → 1200
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1201 → 1492
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:134 → 224
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:233 → 314
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    45. XM_036163876.1 → XP_036019769.1  receptor-type tyrosine-protein phosphatase delta isoform X43

      UniProtKB/TrEMBL
      G3UYU6
      Conserved Domains (7) summary
      cd00063
      Location:317 → 406
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14624
      Location:918 → 1201
      R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
      cd14628
      Location:1202 → 1493
      R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
      pfam07679
      Location:31 → 122
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:39 → 43
      Ig; Ig strand A' [structural motif]
      cd05738
      Location:134 → 224
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:233 → 314
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001014288.2: Suppressed sequence

      Description
      NM_001014288.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q64487.3 GenPept UniProtKB/Swiss-Prot:Q64487

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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