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    Mab21l2 mab-21-like 2 [ Mus musculus (house mouse) ]

    Gene ID: 23937, updated on 27-Nov-2024

    Summary

    Official Symbol
    Mab21l2provided by MGI
    Official Full Name
    mab-21-like 2provided by MGI
    Primary source
    MGI:MGI:1346022
    See related
    Ensembl:ENSMUSG00000057777 AllianceGenome:MGI:1346022
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Acts upstream of or within camera-type eye development; embryonic body morphogenesis; and positive regulation of cell population proliferation. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; embryo mesenchyme; limb; and sensory organ. Human ortholog(s) of this gene implicated in coloboma and syndromic microphthalmia 14. Orthologous to human MAB21L2 (mab-21 like 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    NEW
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    Genomic context

    See Mab21l2 in Genome Data Viewer
    Location:
    3 F1; 3 37.86 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (86453357..86455590, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (86546050..86548283, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene LPS-responsive beige-like anchor Neighboring gene predicted gene, 23850 Neighboring gene predicted gene, 25039 Neighboring gene predicted gene, 31677 Neighboring gene thymosin, beta 10 pseudogene Neighboring gene STARR-seq mESC enhancer starr_08131 Neighboring gene predicted gene, 52625

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011839.4NP_035969.2  protein mab-21-like 2

      See identical proteins and their annotated locations for NP_035969.2

      Status: VALIDATED

      Source sequence(s)
      AK053645, BC058730
      Consensus CDS
      CCDS17447.1
      UniProtKB/Swiss-Prot
      Q8BPP1, Q9R1B2, Q9WVF2
      Related
      ENSMUSP00000159542.1, ENSMUST00000191695.3
      Conserved Domains (1) summary
      pfam03281
      Location:62344
      Mab-21; Mab-21 protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      86453357..86455590 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)