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    Fam3c FAM3 metabolism regulating signaling molecule C [ Mus musculus (house mouse) ]

    Gene ID: 27999, updated on 9-Dec-2024

    Summary

    Official Symbol
    Fam3cprovided by MGI
    Official Full Name
    FAM3 metabolism regulating signaling molecule Cprovided by MGI
    Primary source
    MGI:MGI:107892
    See related
    Ensembl:ENSMUSG00000029672 AllianceGenome:MGI:107892
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ilei; D6Wsu176e
    Summary
    Predicted to enable carbohydrate binding activity. Predicted to be located in Golgi apparatus. Predicted to be active in extracellular space. Is expressed in several structures, including brain; gut; hemolymphoid system gland; liver; and retina. Orthologous to human FAM3C (FAM3 metabolism regulating signaling molecule C). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in frontal lobe adult (RPKM 8.6), bladder adult (RPKM 7.7) and 27 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Fam3c in Genome Data Viewer
    Location:
    6 A3.1; 6 9.24 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (22306519..22356080, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (22306520..22356081, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene cadherin-like and PC-esterase domain containing 1 Neighboring gene STARR-seq mESC enhancer starr_15309 Neighboring gene predicted gene 42573 Neighboring gene STARR-seq mESC enhancer starr_15310 Neighboring gene wingless-type MMTV integration site family, member 16 Neighboring gene STARR-seq mESC enhancer starr_15315 Neighboring gene predicted gene, 38773 Neighboring gene STARR-seq mESC enhancer starr_15316 Neighboring gene STARR-seq mESC enhancer starr_15318 Neighboring gene STARR-seq mESC enhancer starr_15319 Neighboring gene STARR-seq mESC enhancer starr_15321 Neighboring gene STARR-seq mESC enhancer starr_15322 Neighboring gene predicted gene, 38774 Neighboring gene STARR-seq mESC enhancer starr_15323

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Gene trapped (2) 
    • Targeted (2)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables cytokine activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein FAM3C
    Names
    family with sequence similarity 3, member C
    interleukin-like EMT inducer

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_138587.4NP_613053.3  protein FAM3C precursor

      See identical proteins and their annotated locations for NP_613053.3

      Status: PROVISIONAL

      Source sequence(s)
      AC115039
      Consensus CDS
      CCDS39436.1
      UniProtKB/Swiss-Prot
      Q53YY7, Q7TML1, Q91VU0, Q9CTB4
      UniProtKB/TrEMBL
      G5E911
      Related
      ENSMUSP00000127709.2, ENSMUST00000165576.8
      Conserved Domains (1) summary
      cd13940
      Location:53223
      ILEI_FAM3C; Interleukin-like EMT inducer

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      22306519..22356080 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006505102.5XP_006505165.1  protein FAM3C isoform X1

      See identical proteins and their annotated locations for XP_006505165.1

      UniProtKB/Swiss-Prot
      Q53YY7, Q7TML1, Q91VU0, Q9CTB4
      UniProtKB/TrEMBL
      G5E911
      Conserved Domains (1) summary
      cd13940
      Location:53223
      ILEI_FAM3C; Interleukin-like EMT inducer
    2. XM_006505103.5XP_006505166.1  protein FAM3C isoform X1

      See identical proteins and their annotated locations for XP_006505166.1

      UniProtKB/Swiss-Prot
      Q53YY7, Q7TML1, Q91VU0, Q9CTB4
      UniProtKB/TrEMBL
      G5E911
      Conserved Domains (1) summary
      cd13940
      Location:53223
      ILEI_FAM3C; Interleukin-like EMT inducer