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    Serp1 stress-associated endoplasmic reticulum protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 28146, updated on 9-Dec-2024

    Summary

    Official Symbol
    Serp1provided by MGI
    Official Full Name
    stress-associated endoplasmic reticulum protein 1provided by MGI
    Primary source
    MGI:MGI:92638
    See related
    Ensembl:ENSMUSG00000027808 AllianceGenome:MGI:92638
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ramp4; D3Ucla1
    Summary
    Acts upstream of or within several processes, including endoplasmic reticulum unfolded protein response; positive regulation of organ growth; and positive regulation of peptide hormone secretion. Predicted to be located in cytoplasmic microtubule. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including jaw and orbito-sphenoid. Orthologous to human SERP1 (stress associated endoplasmic reticulum protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 190.1), duodenum adult (RPKM 144.7) and 27 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Serp1 in Genome Data Viewer
    Location:
    3 D; 3 28.58 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (58429390..58433305, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (58521969..58525884, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E11710 Neighboring gene predicted gene, 20128 Neighboring gene TSC22 domain family, member 2 Neighboring gene STARR-seq mESC enhancer starr_07749 Neighboring gene STARR-positive B cell enhancer ABC_E1618 Neighboring gene STARR-positive B cell enhancer ABC_E516 Neighboring gene STARR-positive B cell enhancer ABC_E3433 Neighboring gene eukaryotic translation initiation factor 2A Neighboring gene STARR-seq mESC enhancer starr_07753 Neighboring gene STARR-seq mESC enhancer starr_07754 Neighboring gene STARR-positive B cell enhancer ABC_E9549 Neighboring gene selenoprotein T Neighboring gene glutamate rich 6 Neighboring gene predicted gene, 46806

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in cytoplasmic microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic microtubule ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    stress-associated endoplasmic reticulum protein 1
    Names
    ribosome associated membrane protein 4
    ribosome-attached membrane protein 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_030685.3NP_109610.1  stress-associated endoplasmic reticulum protein 1

      See identical proteins and their annotated locations for NP_109610.1

      Status: VALIDATED

      Source sequence(s)
      AI114944, AK149786, CV676503
      Consensus CDS
      CCDS38436.1
      UniProtKB/Swiss-Prot
      Q3TMC9, Q9Z1W5
      Related
      ENSMUSP00000029385.8, ENSMUST00000029385.9
      Conserved Domains (1) summary
      pfam06624
      Location:259
      RAMP4; Ribosome associated membrane protein RAMP4

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      58429390..58433305 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)