U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Sh3bgr SH3-binding domain glutamic acid-rich protein [ Mus musculus (house mouse) ]

    Gene ID: 50795, updated on 9-Dec-2024

    Summary

    Official Symbol
    Sh3bgrprovided by MGI
    Official Full Name
    SH3-binding domain glutamic acid-rich proteinprovided by MGI
    Primary source
    MGI:MGI:1354740
    See related
    Ensembl:ENSMUSG00000040666 AllianceGenome:MGI:1354740
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    5430437A18Rik
    Summary
    Predicted to enable SH3 domain binding activity. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Orthologous to human SH3BGR (SH3 domain binding glutamate rich protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in bladder adult (RPKM 40.7), heart adult (RPKM 35.7) and 8 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Sh3bgr in Genome Data Viewer
    Location:
    16 C4; 16 56.86 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (96001670..96030133)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (96200470..96228933)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene guided entry of tail-anchored proteins factor 1 Neighboring gene Leber congenital amaurosis 5-like Neighboring gene predicted gene, 53923 Neighboring gene STARR-positive B cell enhancer ABC_E7483 Neighboring gene STARR-seq mESC enhancer starr_41616 Neighboring gene UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:96495129-96495238 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:96514185-96514338 Neighboring gene STARR-positive B cell enhancer mm9_chr16:96562962-96563262 Neighboring gene predicted gene, 41510

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Potential readthrough

    Included gene: Get1

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables SH3 domain binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    SH3 domain-binding glutamic acid-rich protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_015825.2NP_056640.1  SH3 domain-binding glutamic acid-rich protein

      Status: VALIDATED

      Source sequence(s)
      AC164647, AC165170
      Consensus CDS
      CCDS28355.1
      UniProtKB/Swiss-Prot
      Q9WUZ7
      UniProtKB/TrEMBL
      Q8R558
      Related
      ENSMUSP00000038110.9, ENSMUST00000048770.16
      Conserved Domains (1) summary
      pfam04908
      Location:198
      SH3BGR; SH3-binding, glutamic acid-rich protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      96001670..96030133
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)