U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Tmem208 transmembrane protein 208 [ Mus musculus (house mouse) ]

    Gene ID: 66320, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tmem208provided by MGI
    Official Full Name
    transmembrane protein 208provided by MGI
    Primary source
    MGI:MGI:1913570
    See related
    Ensembl:ENSMUSG00000014856 AllianceGenome:MGI:1913570
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Hspc171; 1700006C06Rik; 2610030K20Rik
    Summary
    Predicted to be involved in vacuolar protein processing. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in several structures, including adrenal gland; genitourinary system; liver; lung; and spleen. Orthologous to human TMEM208 (transmembrane protein 208). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in duodenum adult (RPKM 31.1), large intestine adult (RPKM 28.4) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Tmem208 in Genome Data Viewer
    Location:
    8 D3; 8 53.04 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (106052980..106062117)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (105326341..105335485)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene engulfment and cell motility 3 Neighboring gene microRNA 328 Neighboring gene F-box and leucine-rich repeat protein 9 Neighboring gene STARR-positive B cell enhancer ABC_E11746 Neighboring gene formin homology 2 domain containing 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:107871965-107872074 Neighboring gene predicted gene, 46049 Neighboring gene solute carrier family 9 (sodium/hydrogen exchanger), member 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Clone Names

    • MGC25457

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in vacuolar protein processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001378965.1NP_001365894.1  transmembrane protein 208 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AC124584
      Conserved Domains (1) summary
      pfam05620
      Location:8162
      DUF788; Protein of unknown function (DUF788)
    2. NM_001378966.1NP_001365895.1  transmembrane protein 208 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC124584
      Related
      ENSMUSP00000096052.3, ENSMUST00000098453.9
      Conserved Domains (1) summary
      pfam05620
      Location:8100
      DUF788; Protein of unknown function (DUF788)
    3. NM_001378967.1NP_001365896.1  transmembrane protein 208 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC124584
      UniProtKB/TrEMBL
      D3Z7S5
      Related
      ENSMUSP00000104997.2, ENSMUST00000109372.3
      Conserved Domains (1) summary
      pfam05620
      Location:8100
      DUF788; Protein of unknown function (DUF788)
    4. NM_001378968.1NP_001365897.1  transmembrane protein 208 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC124584
      UniProtKB/TrEMBL
      S4R1H6
      Related
      ENSMUSP00000138470.2, ENSMUST00000153146.9
      Conserved Domains (1) summary
      pfam05620
      Location:8100
      DUF788; Protein of unknown function (DUF788)
    5. NM_025486.3NP_079762.1  transmembrane protein 208 isoform 3

      See identical proteins and their annotated locations for NP_079762.1

      Status: VALIDATED

      Source sequence(s)
      AC124584
      Consensus CDS
      CCDS22599.1
      UniProtKB/Swiss-Prot
      Q3V2H5, Q8R1F8, Q9CR96
      Related
      ENSMUSP00000015000.5, ENSMUST00000015000.12
      Conserved Domains (1) summary
      pfam05620
      Location:8156
      DUF788; Protein of unknown function (DUF788)

    RNA

    1. NR_166208.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124584
    2. NR_166209.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124584

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      106052980..106062117
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531277.5XP_006531340.1  transmembrane protein 208 isoform X1

      See identical proteins and their annotated locations for XP_006531340.1

      UniProtKB/TrEMBL
      S4R1H6
      Conserved Domains (1) summary
      pfam05620
      Location:8100
      DUF788; Protein of unknown function (DUF788)