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    Surf6 surfeit gene 6 [ Mus musculus (house mouse) ]

    Gene ID: 20935, updated on 9-Dec-2024

    Summary

    Official Symbol
    Surf6provided by MGI
    Official Full Name
    surfeit gene 6provided by MGI
    Primary source
    MGI:MGI:98447
    See related
    Ensembl:ENSMUSG00000036160 AllianceGenome:MGI:98447
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Surf-6; D2Wsu129e
    Summary
    Enables DNA binding activity and RNA binding activity. Acts upstream of or within ribosome biogenesis. Located in granular component and nucleoplasm. Is expressed in several structures, including early conceptus and oocyte. Orthologous to human SURF6 (surfeit 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 11.1), CNS E14 (RPKM 7.6) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Surf6 in Genome Data Viewer
    Location:
    2 A3; 2 19.08 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (26780430..26792899, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (26890418..26902887, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 39774 Neighboring gene ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Neighboring gene STARR-seq mESC enhancer starr_03995 Neighboring gene STARR-seq mESC enhancer starr_03996 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:26758332-26758621 Neighboring gene mediator complex subunit 22 Neighboring gene predicted gene, 23969 Neighboring gene ribosomal protein L7A

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables molecular condensate scaffold activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular condensate scaffold activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in ribosomal large subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosomal small subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosome assembly NAS
    Non-traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within ribosome biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in granular component IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009298.4NP_033324.1  surfeit locus protein 6

      See identical proteins and their annotated locations for NP_033324.1

      Status: VALIDATED

      Source sequence(s)
      AK075636, AK132194, AL773563
      Consensus CDS
      CCDS15812.1
      UniProtKB/Swiss-Prot
      P70279, Q8BPI4, Q8BRL7, Q8R0Q7
      UniProtKB/TrEMBL
      Q3V1X4
      Related
      ENSMUSP00000048457.8, ENSMUST00000047632.14
      Conserved Domains (1) summary
      pfam04935
      Location:186342
      SURF6; Surfeit locus protein 6

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      26780430..26792899 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)