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    K09C6.2 Protein kinase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 187199, updated on 9-Dec-2024

    Summary

    Official Symbol
    K09C6.2
    Official Full Name
    Protein kinase domain-containing protein
    Primary source
    WormBase:WBGene00019556
    Locus tag
    CELE_K09C6.2
    See related
    AllianceGenome:WB:WBGene00019556
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including endocytosis; positive regulation of canonical Wnt signaling pathway; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See K09C6.2 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    14
    Sequence:
    Chromosome: V; NC_003283.11 (856849..862061)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Neuropeptide-Like Protein;Transposase Neighboring gene DUF19 domain-containing protein Neighboring gene tRNA-Ala Neighboring gene ncRNA Neighboring gene DUF19 domain-containing protein Neighboring gene DUF19 domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Protein kinase domain-containing protein
    NP_503344.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      856849..862061
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070943.4NP_503344.2  Protein kinase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      O16946
      Conserved Domains (2) summary
      PTZ00121
      Location:270455
      PTZ00121; MAEBL; Provisional
      COG0515
      Location:72224
      SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]

    RNA

    1. NR_132485.1 RNA Sequence

      Status: REVIEWED

    2. NR_132486.1 RNA Sequence

      Status: REVIEWED

    3. NR_132487.1 RNA Sequence

      Status: REVIEWED

    4. NR_132488.1 RNA Sequence

      Status: REVIEWED