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    Zfp292 zinc finger protein 292 [ Mus musculus (house mouse) ]

    Gene ID: 30046, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zfp292provided by MGI
    Official Full Name
    zinc finger protein 292provided by MGI
    Primary source
    MGI:MGI:1353423
    See related
    Ensembl:ENSMUSG00000039967 AllianceGenome:MGI:1353423
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zfp15; Zn-15; Zn-16; Zfp-15; Krox-10; mKIAA0530; 5730450D02Rik; 5830493J20Rik; 9430062L07Rik
    Summary
    Predicted to enable DNA binding activity and DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; early conceptus; and genitourinary system. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to human ZNF292 (zinc finger protein 292). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in CNS E11.5 (RPKM 6.0), CNS E14 (RPKM 5.7) and 24 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Zfp292 in Genome Data Viewer
    Location:
    4 A5; 4 16.86 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (34803110..34882982, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (34803110..34882983, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_09916 Neighboring gene STARR-seq mESC enhancer starr_09917 Neighboring gene small integral membrane protein 8 Neighboring gene predicted gene, 57497 Neighboring gene STARR-positive B cell enhancer mm9_chr4:34767165-34767465 Neighboring gene tubulin, beta 6 pseudogene Neighboring gene STARR-seq mESC enhancer starr_09922 Neighboring gene STARR-seq mESC enhancer starr_09925 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:34833884-34833993 Neighboring gene STARR-seq mESC enhancer starr_09928 Neighboring gene STARR-seq mESC enhancer starr_09932 Neighboring gene glycoprotein hormones, alpha subunit Neighboring gene pluripotency associated transcript 9

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4)  1 citation
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription activator activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    zinc finger protein 292
    Names
    zinc finger protein 15

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001429838.1NP_001416767.1  zinc finger protein 292 isoform 2

      Status: VALIDATED

      Source sequence(s)
      BX465850, BX649603
    2. NM_013889.3NP_038917.2  zinc finger protein 292 isoform 1

      See identical proteins and their annotated locations for NP_038917.2

      Status: VALIDATED

      Source sequence(s)
      BX465850, BX649603
      Consensus CDS
      CCDS51138.1
      UniProtKB/Swiss-Prot
      B1B0E1, B1B0E2, Q8BQX3, Q8BS87, Q8CGI6, Q922D3, Q9Z2U2
      Related
      ENSMUSP00000037233.6, ENSMUST00000047950.6
      Conserved Domains (3) summary
      COG5189
      Location:17581944
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:724744
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:542561
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      34803110..34882982 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036164179.1XP_036020072.1  zinc finger protein 292 isoform X1

      Conserved Domains (3) summary
      COG5189
      Location:17361922
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:702722
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:520539
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. XM_036164180.1XP_036020073.1  zinc finger protein 292 isoform X1

      Conserved Domains (3) summary
      COG5189
      Location:17361922
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:702722
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:520539
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. XM_036164181.1XP_036020074.1  zinc finger protein 292 isoform X2

      UniProtKB/TrEMBL
      Q8CHF2
      Conserved Domains (1) summary
      sd00017
      Location:734757
      ZF_C2H2; C2H2 Zn finger [structural motif]
    4. XM_006537978.5XP_006538041.1  zinc finger protein 292 isoform X3

      Conserved Domains (3) summary
      COG5048
      Location:567743
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:724744
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:542561
      ZF_C2H2; C2H2 Zn finger [structural motif]